PDB entry 4cd2

View 4cd2 on RCSB PDB site
Description: ligand induced conformational changes in the crystal structures of pneumocystis carinii dihydrofolate reductase complexes with folate and nadp+
Class: oxidoreductase
Keywords: oxido-reductase, folate, oxidoreductase
Deposited on 1999-03-18, released 2000-03-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.176
AEROSPACI score: 0.44 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydrofolate reductase
    Species: Pneumocystis carinii [TaxId:4754]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4cd2a_
  • Heterogens: FOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4cd2A (A:)
mnqqksltlivalttsygigrsnslpwklkkeisyfkrvtsfvptfdsfesmnvvlmgrk
twesiplqfrplkgrinvvitrnesldlgngihsaksldhalellyrtygsessvqinri
fviggaqlykaamdhpkldrimatiiykdihcdvffplkfrdkewssvwkkekhsdlesw
vgtkvphgkinedgfdyefemwtrdl

    Sequence, based on observed residues (ATOM records): (download) 
    >4cd2A (A:)
ksltlivalttsygigrsnslpwklkkeisyfkrvtsfvptfdsfesmnvvlmgrktwes
iplqfrplkgrinvvitrnesldlgngihsaksldhalellyrtygsessvqinrifvig
gaqlykaamdhpkldrimatiiykdihcdvffplkfrdkewssvwkkekhsdleswvgtk
vphgkinedgfdyefemwtrdl