PDB entry 4cbn

View 4cbn on RCSB PDB site
Description: Crystal structure of Complement Factor D mutant R202A after conventional refinement
Class: hydrolase
Keywords: hydrolase, complement system, ensemble refinement
Deposited on 2013-10-15, released 2013-12-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-03-19, with a file datestamp of 2014-03-14.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.1913
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: complement factor d
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00746 (0-227)
      • engineered mutation (201)
    Domains in SCOPe 2.08: d4cbna_
  • Chain 'B':
    Compound: complement factor d
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00746 (0-227)
      • engineered mutation (201)
    Domains in SCOPe 2.08: d4cbnb_
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4cbnA (A:)
ilggreaeaharpymasvqlngahlcggvlvaeqwvlsaahcledaadgkvqvllgahsl
sqpepskrlydvlravphpdsqpdtidhdllllqlsekatlgpavrplpwqrvdrdvapg
tlcdvagwgivnhagrrpdslqhvllpvldratcnrrthhdgaiterlmcaesnrrdsck
gdsggplvcggvlegvvtsgsavcgnrkkpgiytrvasyaawidsvla

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4cbnB (B:)
ilggreaeaharpymasvqlngahlcggvlvaeqwvlsaahcledaadgkvqvllgahsl
sqpepskrlydvlravphpdsqpdtidhdllllqlsekatlgpavrplpwqrvdrdvapg
tlcdvagwgivnhagrrpdslqhvllpvldratcnrrthhdgaiterlmcaesnrrdsck
gdsggplvcggvlegvvtsgsavcgnrkkpgiytrvasyaawidsvla