PDB entry 4cae

View 4cae on RCSB PDB site
Description: Plasmodium vivax N-myristoyltransferase in complex with a benzothiophene inhibitor (compound 20b)
Class: transferase
Keywords: transferase, myristoylation, malaria, inhibitor, benzothiophene
Deposited on 2013-10-08, released 2014-04-02
The last revision prior to the SCOPe 2.05 freeze date was dated 2014-04-09, with a file datestamp of 2014-04-04.
Experiment type: XRAY
Resolution: 1.46 Å
R-factor: 0.2169
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycylpeptide N-tetradecanoyltransferase
    Species: Plasmodium vivax [TaxId:5855]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4caea1
  • Chain 'B':
    Compound: Glycylpeptide N-tetradecanoyltransferase
    Species: Plasmodium vivax [TaxId:5855]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4caeb1
  • Chain 'C':
    Compound: Glycylpeptide N-tetradecanoyltransferase
    Species: Plasmodium vivax [TaxId:5855]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4caec1
  • Heterogens: MG, CL, 3F3, DMS, NHW, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4caeA (A:)
dykfwytqpvpkindefnesvnepfisdnkvedvrkdeyklppgyswyvcdvkdekdrse
iytlltdnyvedddnifrfnysaefllwaltspnylktwhigvkydasnkligfisaipt
dicihkrtikmaevnflcvhktlrskrlapvlikeitrrinleniwqaiytagvylpkpv
sdaryyhrsinvkklieigfsslnsrltmsraiklyrvedtlniknmrlmkkkdvegvhk
llgsyleqfnlyavftkeeiahwflpienviytyvneengkikdmisfyslpsqilgndk
ystlnaaysfynvtttatfkqlmqdaillakrnnfdvfnalevmqnksvfedlkfgegdg
slkyylynwkcasfapahvgivll

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4caeB (B:)
dykfwytqpvpkindefnesvnepfisdnkvedvrkdeyklppgyswyvcdvkdekdrse
iytlltdnyvedddnifrfnysaefllwaltspnylktwhigvkydasnkligfisaipt
dicihkrtikmaevnflcvhktlrskrlapvlikeitrrinleniwqaiytagvylpkpv
sdaryyhrsinvkklieigfsslnsrltmsraiklyrvedtlniknmrlmkkkdvegvhk
llgsyleqfnlyavftkeeiahwflpienviytyvneengkikdmisfyslpsqilgndk
ystlnaaysfynvtttatfkqlmqdaillakrnnfdvfnalevmqnksvfedlkfgegdg
slkyylynwkcasfapahvgivll

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4caeC (C:)
dykfwytqpvpkindefnesvnepfisdnkvedvrkdeyklppgyswyvcdvkdekdrse
iytlltdnyvedddnifrfnysaefllwaltspnylktwhigvkydasnkligfisaipt
dicihkrtikmaevnflcvhktlrskrlapvlikeitrrinleniwqaiytagvylpkpv
sdaryyhrsinvkklieigfsslnsrltmsraiklyrvedtlniknmrlmkkkdvegvhk
llgsyleqfnlyavftkeeiahwflpienviytyvneengkikdmisfyslpsqilgndk
ystlnaaysfynvtttatfkqlmqdaillakrnnfdvfnalevmqnksvfedlkfgegdg
slkyylynwkcasfapahvgivll

    Sequence, based on observed residues (ATOM records): (download) 
    >4caeC (C:)
dykfwytqpvpkindefnesvnepfisdnkvedvrkdeyklppgyswyvcdvkdekdrse
iytlltdnyvedddnifrfnysaefllwaltspnylktwhigvkydasnkligfisaipt
dicihkrtikmaevnflcvhktlrskrlapvlikeitrrinleniwqaiytagvylpkpv
sdaryyhrsinvkklieigfvedtlniknmrlmkkkdvegvhkllgsyleqfnlyavftk
eeiahwflpienviytyvneengkikdmisfyslpsqilgndkystlnaaysfynvttta
tfkqlmqdaillakrnnfdvfnalevmqnksvfedlkfgegdgslkyylynwkcasfapa
hvgivll