PDB entry 4c9w

View 4c9w on RCSB PDB site
Description: Crystal structure of NUDT1 (MTH1) with R-crizotinib
Class: hydrolase
Keywords: hydrolase, crizotinib
Deposited on 2013-10-03, released 2014-04-02
The last revision prior to the SCOPe 2.03 freeze date was dated 2014-04-02, with a file datestamp of 2014-03-28.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: 0.152
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 7,8-dihydro-8-oxoguanine triphosphatase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d4c9wa_
  • Heterogens: CL, VGH, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4c9wA (A:)
gamgasrlytlvlvlqpqrvllgmkkrgfgagrwngfggkvqegetiedgarrelqeesg
ltvdalhkvgqivfefvgepelmdvhvfctdsiqgtpvesdemrpcwfqldqipfkdmwp
ddsywfplllqkkkfhgyfkfqgqdtildytlrevdtv

    Sequence, based on observed residues (ATOM records): (download) 
    >4c9wA (A:)
asrlytlvlvlqpqrvllgmkkrgfgagrwngfggkvqegetiedgarrelqeesgltvd
alhkvgqivfefvgepelmdvhvfctdsiqgtpvesdemrpcwfqldqipfkdmwpddsy
wfplllqkkkfhgyfkfqgqdtildytlrevdtv