PDB entry 4c5r

View 4c5r on RCSB PDB site
Description: Structural Investigations into the Stereochemistry and Activity of a Phenylalanine-2,3-Aminomutase from Taxus chinensis
Class: lyase
Keywords: lyase, (r)-beta-phenylalanine analogue
Deposited on 2013-09-16, released 2014-05-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-23, with a file datestamp of 2019-10-18.
Experiment type: XRAY
Resolution: 2.14 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: phenylalanine ammonia-lyase
    Species: TAXUS WALLICHIANA VAR. CHINENSIS [TaxId:29808]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q68G84
      • chromophore (194)
    Domains in SCOPe 2.08: d4c5ra_
  • Chain 'B':
    Compound: phenylalanine ammonia-lyase
    Species: TAXUS WALLICHIANA VAR. CHINENSIS [TaxId:29808]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q68G84
      • chromophore (194)
    Domains in SCOPe 2.08: d4c5rb_
  • Chain 'C':
    Compound: phenylalanine ammonia-lyase
    Species: TAXUS WALLICHIANA VAR. CHINENSIS [TaxId:29808]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q68G84
      • chromophore (194)
    Domains in SCOPe 2.08: d4c5rc_
  • Chain 'D':
    Compound: phenylalanine ammonia-lyase
    Species: TAXUS WALLICHIANA VAR. CHINENSIS [TaxId:29808]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q68G84
      • chromophore (194)
    Domains in SCOPe 2.08: d4c5rd_
  • Heterogens: BQ7, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4c5rA (A:)
mgsshhhhhhssglvprgshmgfavesrshvkdilglinafnevkkitvdgttpitvahv
aalarrhdvkvaleaeqcrarvetcsswvqrkaedgadiygvttgfgacssrrtnrlsel
qeslircllagvftkgcapsvdelpatatrsamllrlnsftygcsgirwevmealeklln
snvspkvplrgsvsasgdliplayiaglligkpsviarigddvevpapealsrvglrpfk
lqakeglalvngtsfatavastvmydanvllllvetlcgmfcevifgreefahplihkvk
phpgqiesaellewllrsspfqelsreyysidklkkpkqdryalrsspqwlaplvqtird
atttvetevnsandnpiidhandralhganfqgsavgfymdyvriavaglgkllfaqfte
lmieyysnglpgnlslgpdlsvdyglkgldiamaaysselqylanpvtthvhsaeqhnqd
inslalisarkteealdilklmiashltamcqavdlrqleealvkvvenvvstladecgl
pndtkarllyvakavpvytylespcdptlplllglkqscfdtilalhkkdgietdtlvdr
laefekrlsdrlenemtavrvlyekkghktadnndalvriqgskflpfyrfvreeldtgv
msarreqtpqedvqkvfdaiadgritvpllhclqgflgqpngcangv

    Sequence, based on observed residues (ATOM records): (download) 
    >4c5rA (A:)
shvkdilglinafnevkkitvdgttpitvahvaalarrhdvkvaleacrarvetcsswvq
rkaedgadiygvttgfgacssrrtnrlselqeslircllagvftelpatatrsamllrln
sftygcsgirwevmealekllnsnvspkvplrgsvsasgdliplayiaglligkpsviar
igddvevpapealsrvglrpfklqakeglalvngtsfatavastvmydanvllllvetlc
gmfcevifgreefahplihkvkphpgqiesaellewllrsspfqelsreyysidklkkpk
qdryalrsspqwlaplvqtirdatttvetevnsandnpiidhandralhganfqgsavgf
ymdyvriavaglgkllfaqftelmieyysnglpgnlslgpdlsvdyglkgldiamaayss
elqylanpvtthvhsaeqhnqdinslalisarkteealdilklmiashltamcqavdlrq
leealvkvvenvvstladecglpndtkarllyvakavpvytylespcdptlplllglkqs
cfdtilaltlvdrlaefekrlsdrlenemtavrvlyevriqgskflpfyrfvreeldtgv
msarreqtpqedvqkvfdaiadgritvpllhclqgfl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4c5rB (B:)
mgsshhhhhhssglvprgshmgfavesrshvkdilglinafnevkkitvdgttpitvahv
aalarrhdvkvaleaeqcrarvetcsswvqrkaedgadiygvttgfgacssrrtnrlsel
qeslircllagvftkgcapsvdelpatatrsamllrlnsftygcsgirwevmealeklln
snvspkvplrgsvsasgdliplayiaglligkpsviarigddvevpapealsrvglrpfk
lqakeglalvngtsfatavastvmydanvllllvetlcgmfcevifgreefahplihkvk
phpgqiesaellewllrsspfqelsreyysidklkkpkqdryalrsspqwlaplvqtird
atttvetevnsandnpiidhandralhganfqgsavgfymdyvriavaglgkllfaqfte
lmieyysnglpgnlslgpdlsvdyglkgldiamaaysselqylanpvtthvhsaeqhnqd
inslalisarkteealdilklmiashltamcqavdlrqleealvkvvenvvstladecgl
pndtkarllyvakavpvytylespcdptlplllglkqscfdtilalhkkdgietdtlvdr
laefekrlsdrlenemtavrvlyekkghktadnndalvriqgskflpfyrfvreeldtgv
msarreqtpqedvqkvfdaiadgritvpllhclqgflgqpngcangv

    Sequence, based on observed residues (ATOM records): (download) 
    >4c5rB (B:)
shvkdilglinafnevkkitvdgttpitvahvaalarrhdvkvaleacrarvetcsswvq
rkaedgadiygvttgfgacssrrtnrlselqeslircllagvftvdelpatatrsamllr
lnsftygcsgirwevmealekllnsnvspkvplrgsvsasgdliplayiaglligkpsvi
arigddvevpapealsrvglrpfklqakeglalvngtsfatavastvmydanvllllvet
lcgmfcevifgreefahplihkvkphpgqiesaellewllrsspfqelsreyysidklkk
pkqdryalrsspqwlaplvqtirdatttvetevnsandnpiidhandralhganfqgsav
gfymdyvriavaglgkllfaqftelmieyysnglpgnlslgpdlsvdyglkgldiamaay
sselqylanpvtthvhsaeqhnqdinslalisarkteealdilklmiashltamcqavdl
rqleealvkvvenvvstladecglpndtkarllyvakavpvytylespcdptlplllglk
qscfdtilalhtdtlvdrlaefekrlsdrlenemtavrvlyekvriqgskflpfyrfvre
eldtgvmsarreqtpqedvqkvfdaiadgritvpllhclqgf

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4c5rC (C:)
mgsshhhhhhssglvprgshmgfavesrshvkdilglinafnevkkitvdgttpitvahv
aalarrhdvkvaleaeqcrarvetcsswvqrkaedgadiygvttgfgacssrrtnrlsel
qeslircllagvftkgcapsvdelpatatrsamllrlnsftygcsgirwevmealeklln
snvspkvplrgsvsasgdliplayiaglligkpsviarigddvevpapealsrvglrpfk
lqakeglalvngtsfatavastvmydanvllllvetlcgmfcevifgreefahplihkvk
phpgqiesaellewllrsspfqelsreyysidklkkpkqdryalrsspqwlaplvqtird
atttvetevnsandnpiidhandralhganfqgsavgfymdyvriavaglgkllfaqfte
lmieyysnglpgnlslgpdlsvdyglkgldiamaaysselqylanpvtthvhsaeqhnqd
inslalisarkteealdilklmiashltamcqavdlrqleealvkvvenvvstladecgl
pndtkarllyvakavpvytylespcdptlplllglkqscfdtilalhkkdgietdtlvdr
laefekrlsdrlenemtavrvlyekkghktadnndalvriqgskflpfyrfvreeldtgv
msarreqtpqedvqkvfdaiadgritvpllhclqgflgqpngcangv

    Sequence, based on observed residues (ATOM records): (download) 
    >4c5rC (C:)
shvkdilglinafnevkkitvdgttpitvahvaalarrhdvkvaleacrarvetcsswvq
rkaedgadiygvttgfgacssrrtnrlselqeslircllagvftdelpatatrsamllrl
nsftygcsgirwevmealekllnsnvspkvplrgsvsasgdliplayiaglligkpsvia
rigddvevpapealsrvglrpfklqakeglalvngtsfatavastvmydanvllllvetl
cgmfcevifgreefahplihkvkphpgqiesaellewllrsspfqelsreyysidklkkp
kqdryalrsspqwlaplvqtirdatttvetevnsandnpiidhandralhganfqgsavg
fymdyvriavaglgkllfaqftelmieyysnglpgnlslgpdlsvdyglkgldiamaays
selqylanpvtthvhsaeqhnqdinslalisarkteealdilklmiashltamcqavdlr
qleealvkvvenvvstladecglpndtkarllyvakavpvytylespcdptlplllglkq
scfdtilalhtdtlvdrlaefekrlsdrlenemtavrvlyekvriqgskflpfyrfvree
ldtgvmsarreqtpqedvqkvfdaiadgritvpllhclqgfl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4c5rD (D:)
mgsshhhhhhssglvprgshmgfavesrshvkdilglinafnevkkitvdgttpitvahv
aalarrhdvkvaleaeqcrarvetcsswvqrkaedgadiygvttgfgacssrrtnrlsel
qeslircllagvftkgcapsvdelpatatrsamllrlnsftygcsgirwevmealeklln
snvspkvplrgsvsasgdliplayiaglligkpsviarigddvevpapealsrvglrpfk
lqakeglalvngtsfatavastvmydanvllllvetlcgmfcevifgreefahplihkvk
phpgqiesaellewllrsspfqelsreyysidklkkpkqdryalrsspqwlaplvqtird
atttvetevnsandnpiidhandralhganfqgsavgfymdyvriavaglgkllfaqfte
lmieyysnglpgnlslgpdlsvdyglkgldiamaaysselqylanpvtthvhsaeqhnqd
inslalisarkteealdilklmiashltamcqavdlrqleealvkvvenvvstladecgl
pndtkarllyvakavpvytylespcdptlplllglkqscfdtilalhkkdgietdtlvdr
laefekrlsdrlenemtavrvlyekkghktadnndalvriqgskflpfyrfvreeldtgv
msarreqtpqedvqkvfdaiadgritvpllhclqgflgqpngcangv

    Sequence, based on observed residues (ATOM records): (download) 
    >4c5rD (D:)
shvkdilglinafnevkkitvdgttpitvahvaalarrhdvkvaleacrarvetcsswvq
rkaedgadiygvttgfgacssrrtnrlselqeslircllagvftdelpatatrsamllrl
nsftygcsgirwevmealekllnsnvspkvplrgsvsasgdliplayiaglligkpsvia
rigddvevpapealsrvglrpfklqakeglalvngtsfatavastvmydanvllllvetl
cgmfcevifgreefahplihkvkphpgqiesaellewllrsspfqelsreyysidklkkp
kqdryalrsspqwlaplvqtirdatttvetevnsandnpiidhandralhganfqgsavg
fymdyvriavaglgkllfaqftelmieyysnglpgnlslgpdlsvdyglkgldiamaays
selqylanpvtthvhsaeqhnqdinslalisarkteealdilklmiashltamcqavdlr
qleealvkvvenvvstladecglpndtkarllyvakavpvytylespcdptlplllglkq
scfdtilaldtlvdrlaefekrlsdrlenemtavrvlyeriqgskflpfyrfvreeldtg
vmsarreqtpqedvqkvfdaiadgritvpllhclqgfl