PDB entry 4c5d

View 4c5d on RCSB PDB site
Description: Crystal structure of Bcl-xL in complex with benzoylurea compound (42)
Class: apoptosis
Keywords: apoptosis, bcl-2
Deposited on 2013-09-11, released 2014-02-05
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-03-12, with a file datestamp of 2014-03-07.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.1699
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bcl-2-like protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07817 (31-End)
      • expression tag (0-4)
    Domains in SCOPe 2.08: d4c5da1, d4c5da2
  • Chain 'B':
    Compound: Bcl-2-like protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07817 (31-End)
      • expression tag (2-4)
    Domains in SCOPe 2.08: d4c5db1, d4c5db2
  • Heterogens: X0R, SO4, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4c5dA (A:)
gplgsmsqsnrelvvdflsyklsqkgyswsqmaavkqalreagdefelryrrafsdltsq
lhitpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawma
tylndhlepwiqenggwdtfvelygnnaaaesrkgqer

    Sequence, based on observed residues (ATOM records): (download) 
    >4c5dA (A:)
gplgsmsqsnrelvvdflsyklsqkgyswsqmaavkqalreagdefelryrrafsdltsq
lhitpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawma
tylndhlepwiqenggwdtfvelyg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4c5dB (B:)
gplgsmsqsnrelvvdflsyklsqkgyswsqmaavkqalreagdefelryrrafsdltsq
lhitpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawma
tylndhlepwiqenggwdtfvelygnnaaaesrkgqer

    Sequence, based on observed residues (ATOM records): (download) 
    >4c5dB (B:)
lgsmsqsnrelvvdflsyklsqkgyswsqmaavkqalreagdefelryrrafsdltsqlh
itpgtayqsfeqvvnelfrdgvnwgrivaffsfggalcvesvdkemqvlvsriaawmaty
lndhlepwiqenggwdtfvelygnn