PDB entry 4c4z

View 4c4z on RCSB PDB site
Description: Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with A8
Class: hydrolase
Keywords: hydrolase, drug design, multiple binding modes
Deposited on 2013-09-09, released 2014-10-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-24, with a file datestamp of 2021-02-19.
Experiment type: XRAY
Resolution: 2.06 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bifunctional epoxide hydrolase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c4za_
  • Chain 'B':
    Compound: Bifunctional epoxide hydrolase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c4zb_
  • Heterogens: W9L, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4c4zA (A:)
tscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrvl
amdmkgygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfyp
ervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfkslf
rasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrnm
ernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqmd
kptevnqilikwldsdarnppvvskm

    Sequence, based on observed residues (ATOM records): (download) 
    >4c4zA (A:)
tscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrvl
amdmkgygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfyp
ervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfkslf
rasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrnm
ernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqmd
kptevnqilikwldsdar

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4c4zB (B:)
tscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrvl
amdmkgygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfyp
ervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfkslf
rasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrnm
ernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqmd
kptevnqilikwldsdarnppvvskm

    Sequence, based on observed residues (ATOM records): (download) 
    >4c4zB (B:)
tscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrvl
amdmkgygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfyp
ervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfkslf
rasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrnm
ernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqmd
kptevnqilikwldsdar