PDB entry 4c4x

View 4c4x on RCSB PDB site
Description: Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with C9
Class: hydrolase
Keywords: hydrolase, drug design, multiple binding modes
Deposited on 2013-09-09, released 2014-10-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-24, with a file datestamp of 2021-02-19.
Experiment type: XRAY
Resolution: 2.17 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bifunctional epoxide hydrolase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c4xa_
  • Chain 'B':
    Compound: Bifunctional epoxide hydrolase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4c4xb_
  • Heterogens: W9M, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4c4xA (A:)
tscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrvl
amdmkgygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfyp
ervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfkslf
rasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrnm
ernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqmd
kptevnqilikwldsdarnppvvskm

    Sequence, based on observed residues (ATOM records): (download) 
    >4c4xA (A:)
sdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrvlamdmk
gygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfypervra
vaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfkslfrasde
svlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrnmernwk
wackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqmdkptev
nqilikwldsdar

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4c4xB (B:)
tscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrvl
amdmkgygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfyp
ervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfkslf
rasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrnm
ernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqmd
kptevnqilikwldsdarnppvvskm

    Sequence, based on observed residues (ATOM records): (download) 
    >4c4xB (B:)
psdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrvlamdm
kgygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfypervr
avaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfkslfrasd
esvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrnmernw
kwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqmdkpte
vnqilikwldsdar