PDB entry 4c3f
View 4c3f on RCSB PDB site
Description: Structure of Lck in complex with a compound discovered by Virtual Fragment Linking
Class: transferase
Keywords: transferase
Deposited on
2013-08-23, released
2013-10-23
The last revision prior to the SCOPe 2.05 freeze date was dated
2014-01-15, with a file datestamp of
2014-01-10.
Experiment type: XRAY
Resolution: 1.72 Å
R-factor: 0.17953
AEROSPACI score: 0.47
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Tyrosine-protein kinase Lck
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P06239
- engineered mutation (129)
Domains in SCOPe 2.05: d4c3fa_ - Heterogens: 7KW, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4c3fA (A:)
gpewevpretlklverlgagqfgevwmgyynghtkvavkslkqgsmspdaflaeanlmkq
lqhqrlvrlyavvtqepiyiiteymengslvdflktpsgikltinklldmaaqiaegmaf
ieernyihrnlraanilvsdtlsckiadfglarliedneytaregakfpikwtapeainy
gtftiksdvwsfgillteivthgripypgmtnpeviqnlergyrmvrpdncpeelyqlmr
lcwkerpedrptfdylrsvledfftat
Sequence, based on observed residues (ATOM records): (download)
>4c3fA (A:)
wevpretlklverlgagqfgevwmgyynghtkvavkslkqgsmspdaflaeanlmkqlqh
qrlvrlyavvtqepiyiiteymengslvdflktpsgikltinklldmaaqiaegmafiee
rnyihrnlraanilvsdtlsckiadfglarliedneytarfpikwtapeainygtftiks
dvwsfgillteivthgripypgmtnpeviqnlergyrmvrpdncpeelyqlmrlcwkerp
edrptfdylrsvledff