PDB entry 4c2m

View 4c2m on RCSB PDB site
Description: Structure of RNA polymerase I at 2.8 A resolution
Class: transcription
Keywords: transcription, ribosome biogenesis
Deposited on 2013-08-19, released 2013-10-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2015-08-19, with a file datestamp of 2015-08-14.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '1':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 4
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4c2m1_
  • Chain '2':
    Compound: DNA-directed RNA polymerase I subunit RPA49
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain '3':
    Compound: DNA-directed RNA polymerase I subunit RPA34
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain '4':
    Compound: DNA-directed RNA polymerase I subunit rpa43
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'A':
    Compound: DNA-directed RNA polymerase I subunit rpa190
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: DNA-directed RNA polymerase I subunit rpa135
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: DNA-directed RNA polymerases I and III subunit rpac1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: DNA-directed RNA polymerase I subunit rpa14
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4c2me1, d4c2me2
  • Chain 'F':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4c2mf_
  • Chain 'G':
    Compound: DNA-directed RNA polymerase I subunit rpa43
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 3
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4c2mh_
  • Chain 'I':
    Compound: DNA-directed RNA polymerase I subunit rpa12
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 5
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4c2mj_
  • Chain 'K':
    Compound: DNA-directed RNA polymerases I and III subunit rpac2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4c2mk_
  • Chain 'L':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 4
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4c2ml_
  • Chain 'M':
    Compound: DNA-directed RNA polymerase I subunit RPA49
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'N':
    Compound: DNA-directed RNA polymerase I subunit RPA34
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'O':
    Compound: DNA-directed RNA polymerase I subunit rpa43
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: DNA-directed RNA polymerase I subunit rpa190
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Q':
    Compound: DNA-directed RNA polymerase I subunit rpa135
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'R':
    Compound: DNA-directed RNA polymerases I and III subunit rpac1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'S':
    Compound: DNA-directed RNA polymerase I subunit rpa14
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'T':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 1
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4c2mt1, d4c2mt2
  • Chain 'U':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4c2mu_
  • Chain 'V':
    Compound: DNA-directed RNA polymerase I subunit rpa43
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'W':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 3
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4c2mw_
  • Chain 'X':
    Compound: DNA-directed RNA polymerase I subunit rpa12
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Y':
    Compound: DNA-directed RNA polymerases I, II, and III subunit rpabc 5
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4c2my_
  • Chain 'Z':
    Compound: DNA-directed RNA polymerases I and III subunit rpac2
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4c2mz_
  • Heterogens: ZN, SO4, HOH

PDB Chain Sequences:

  • Chain '1':
    Sequence, based on SEQRES records: (download)
    >4c2m1 (1:)
    msregfqiptnldaaaagtsqartatlkyicaecssklslsrtdavrckdcghrillkar
    tkrlvqfear
    

    Sequence, based on observed residues (ATOM records): (download)
    >4c2m1 (1:)
    lkyicaecssklslsrtdavrckdcghrillkartkrlvqfear
    

  • Chain '2':
    No sequence available.

  • Chain '3':
    No sequence available.

  • Chain '4':
    No sequence available.

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >4c2mE (E:)
    mdqenernisrlwrafrtvkemvkdrgyfitqeevelpledfkakycdsmgrpqrkmmsf
    qanpteesiskfpdmgslwvefcdepsvgvktmktfvihiqeknfqtgifvyqnnitpsa
    mklvpsippatietfneaalvvnithhelvpkhirlssdekrellkryrlkesqlpriqr
    adpvalylglkrgevvkiirksetsgryasyricm
    

    Sequence, based on observed residues (ATOM records): (download)
    >4c2mE (E:)
    enernisrlwrafrtvkemvkdrgyfitqeevelpledfkakycdsmgrpqrkmmsfqan
    pteesiskfpdmgslwvefcdepsvgvktmktfvihiqeknfqtgifvyqnnitpsamkl
    vpsippatietfneaalvvnithhelvpkhirlssdekrellkryrlkesqlpriqradp
    valylglkrgevvkiirksetsgryasyricm
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >4c2mF (F:)
    msdyeeafndgnenfedfdvehfsdeetyeekpqfkdgettdangktivtggngpedfqq
    heqirrktlkekaipkdqrattpymtkyerarilgtralqismnapvfvdlegetdplri
    amkelaekkiplvirrylpdgsfedwsveelivdl
    

    Sequence, based on observed residues (ATOM records): (download)
    >4c2mF (F:)
    pedfqqheqirrktlkekaipkdqrattpymtkyerarilgtralqismnapvfvdlege
    tdplriamkelaekkiplvirrylpdgsfedwsveelivd
    

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >4c2mH (H:)
    msntlfddifqvsevdpgrynkvcrieaasttqdqckltldinvelfpvaaqdsltvtia
    sslnledtpandssatrswrppqagdrsladdydyvmygtaykfeevskdliavyysfgg
    llmrlegnyrnlnnlkqenayllirr
    

    Sequence, based on observed residues (ATOM records): (download)
    >4c2mH (H:)
    ntlfddifqvsevdpgrynkvcrieaasttqdqckltldinvelfpvaaqdsltvtiass
    lnswrppqagdrsladdydyvmygtaykfeevskdliavyysfggllmrlegnyrnlnnl
    kqenayllirr
    

  • Chain 'I':
    No sequence available.

  • Chain 'J':
    Sequence, based on SEQRES records: (download)
    >4c2mJ (J:)
    mivpvrcfscgkvvgdkwesylnllqedeldegtalsrlglkryccrrmilthvdliekf
    lrynplekrd
    

    Sequence, based on observed residues (ATOM records): (download)
    >4c2mJ (J:)
    mivpvrcfscgkvvgdkwesylnllqedeldegtalsrlglkryccrrmilthvdliekf
    lrynplekr
    

  • Chain 'K':
    Sequence, based on SEQRES records: (download)
    >4c2mK (K:)
    mtedieqkktatevtpqepkhiqeeeeqdvdmtgdeeqeeepdrekiklltqatsedgts
    asfqiveedhtlgnalryvimknpdvefcgysiphpsenllniriqtygettavdalqkg
    lkdlmdlcdvveskftekiksm
    

    Sequence, based on observed residues (ATOM records): (download)
    >4c2mK (K:)
    pdrekiklltqatsedgtsasfqiveedhtlgnalryvimknpdvefcgysiphpsenll
    niriqtygettavdalqkglkdlmdlcdvveskftekiksm
    

  • Chain 'L':
    Sequence, based on SEQRES records: (download)
    >4c2mL (L:)
    msregfqiptnldaaaagtsqartatlkyicaecssklslsrtdavrckdcghrillkar
    tkrlvqfear
    

    Sequence, based on observed residues (ATOM records): (download)
    >4c2mL (L:)
    lkyicaecssklslsrtdavrckdcghrillkartkrlvqfear
    

  • Chain 'M':
    No sequence available.

  • Chain 'N':
    No sequence available.

  • Chain 'O':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.

  • Chain 'R':
    No sequence available.

  • Chain 'S':
    No sequence available.

  • Chain 'T':
    Sequence, based on SEQRES records: (download)
    >4c2mT (T:)
    mdqenernisrlwrafrtvkemvkdrgyfitqeevelpledfkakycdsmgrpqrkmmsf
    qanpteesiskfpdmgslwvefcdepsvgvktmktfvihiqeknfqtgifvyqnnitpsa
    mklvpsippatietfneaalvvnithhelvpkhirlssdekrellkryrlkesqlpriqr
    adpvalylglkrgevvkiirksetsgryasyricm
    

    Sequence, based on observed residues (ATOM records): (download)
    >4c2mT (T:)
    enernisrlwrafrtvkemvkdrgyfitqeevelpledfkakycdsmgrpqrkmmsfqan
    pteesiskfpdmgslwvefcdepsvgvktmktfvihiqeknfqtgifvyqnnitpsamkl
    vpsippatietfneaalvvnithhelvpkhirlssdekrellkryrlkesqlpriqradp
    valylglkrgevvkiirksetsgryasyricm
    

  • Chain 'U':
    Sequence, based on SEQRES records: (download)
    >4c2mU (U:)
    msdyeeafndgnenfedfdvehfsdeetyeekpqfkdgettdangktivtggngpedfqq
    heqirrktlkekaipkdqrattpymtkyerarilgtralqismnapvfvdlegetdplri
    amkelaekkiplvirrylpdgsfedwsveelivdl
    

    Sequence, based on observed residues (ATOM records): (download)
    >4c2mU (U:)
    pedfqqheqirrktlkekaipkdqrattpymtkyerarilgtralqismnapvfvdlege
    tdplriamkelaekkiplvirrylpdgsfedwsveelivd
    

  • Chain 'V':
    No sequence available.

  • Chain 'W':
    Sequence, based on SEQRES records: (download)
    >4c2mW (W:)
    msntlfddifqvsevdpgrynkvcrieaasttqdqckltldinvelfpvaaqdsltvtia
    sslnledtpandssatrswrppqagdrsladdydyvmygtaykfeevskdliavyysfgg
    llmrlegnyrnlnnlkqenayllirr
    

    Sequence, based on observed residues (ATOM records): (download)
    >4c2mW (W:)
    ntlfddifqvsevdpgrynkvcrieaasttqdqckltldinvelfpvaaqdsltvtiass
    lnswrppqagdrsladdydyvmygtaykfeevskdliavyysfggllmrlegnyrnlnnl
    kqenayllirr
    

  • Chain 'X':
    No sequence available.

  • Chain 'Y':
    Sequence, based on SEQRES records: (download)
    >4c2mY (Y:)
    mivpvrcfscgkvvgdkwesylnllqedeldegtalsrlglkryccrrmilthvdliekf
    lrynplekrd
    

    Sequence, based on observed residues (ATOM records): (download)
    >4c2mY (Y:)
    mivpvrcfscgkvvgdkwesylnllqedeldegtalsrlglkryccrrmilthvdliekf
    lrynplekr
    

  • Chain 'Z':
    Sequence, based on SEQRES records: (download)
    >4c2mZ (Z:)
    mtedieqkktatevtpqepkhiqeeeeqdvdmtgdeeqeeepdrekiklltqatsedgts
    asfqiveedhtlgnalryvimknpdvefcgysiphpsenllniriqtygettavdalqkg
    lkdlmdlcdvveskftekiksm
    

    Sequence, based on observed residues (ATOM records): (download)
    >4c2mZ (Z:)
    drekiklltqatsedgtsasfqiveedhtlgnalryvimknpdvefcgysiphpsenlln
    iriqtygettavdalqkglkdlmdlcdvveskftekiksm