PDB entry 4c02
View 4c02 on RCSB PDB site
Description: Crystal structure of human ACVR1 (ALK2) in complex with FKBP12.6 and dorsomorphin
Class: transferase/isomerase
Keywords: transferase-isomerase complex, transferase, dorsomorphin,
Deposited on
2013-07-31, released
2013-08-07
The last revision prior to the SCOPe 2.07 freeze date was dated
2013-08-07, with a file datestamp of
2013-08-02.
Experiment type: XRAY
Resolution: 2.17 Å
R-factor: 0.17833
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Activin receptor type-1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4c02a_ - Chain 'B':
Compound: peptidyl-prolyl cis-trans isomerase fkbp1b
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4c02b_ - Heterogens: FLC, TAK, EDO, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4c02A (A:)
smttnvgdstladlldhsctsgsgsglpflvqrtvarqitllecvgkgrygevwrgswqg
envavkifssrdekswfretelyntvmlrhenilgfiasdmtsrhsstqlwlithyhemg
slydylqlttldtvsclrivlsiasglahlhieifgtqgkpaiahrdlksknilvkkngq
cciadlglavmhsqstnqldvgnnprvgtkrymapevldetiqvdcfdsykrvdiwafgl
vlwevarrmvsngivedykppfydvvpndpsfedmrkvvcvdqqrpnipnrwfsdptlts
laklmkecwyqnpsarltalrikktltkid
Sequence, based on observed residues (ATOM records): (download)
>4c02A (A:)
stladlldsgsgsglpflvqrtvarqitllecvgkgrygevwrgswqgenvavkifssrd
ekswfretelyntvmlrhenilgfiasdmtsrstqlwlithyhemgslydylqlttldtv
sclrivlsiasglahlhieifgtqgkpaiahrdlksknilvkkngqcciadlglavmhsq
stnqldvprvgtkrymapevldetiqvdcfdsykrvdiwafglvlwevarrmvsngived
ykppfydvvpndpsfedmrkvvcvdqqrpnipnrwfsdptltslaklmkecwyqnpsarl
talrikktltkid
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4c02B (B:)
mgveietispgdgrtfpkkgqtcvvhytgmlqngkkfdssrdrnkpfkfrigkqevikgf
eegaaqmslgqrakltctpdvaygatghpgvippnatlifdvellnle