PDB entry 4byi
View 4byi on RCSB PDB site
Description: Aurora A kinase bound to a highly selective imidazopyridine inhibitor
Class: transferase
Keywords: transferase, cell cycle, inhibitor
Deposited on
2013-07-19, released
2013-11-20
The last revision prior to the SCOPe 2.03 freeze date was dated
2013-11-20, with a file datestamp of
2013-11-15.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.2284
AEROSPACI score: 0.22
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Aurora kinase A
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.03: d4byia_ - Heterogens: FH3
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4byiA (A:)
gameskkrqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehql
rreveiqshlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyit
elanalsychskrvihrdikpenlllgsagelkiadfgwsvhapssrrttlcgtldylpp
emiegrmhdekvdlwslgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegard
lisrllkhnpsqrpmlrevlehpwitansskpsncqnkesaskqs
Sequence, based on observed residues (ATOM records): (download)
>4byiA (A:)
rqwaledfeigrplgkgkfgnvylarekqskfilalkvlfkaqlekagvehqlrreveiq
shlrhpnilrlygyfhdatrvylileyaplgtvyrelqklskfdeqrtatyitelanals
ychskrvihrdikpenlllgsagelkiadfgwsvhagtldylppemiegrmhdekvdlws
lgvlcyeflvgkppfeantyqetykrisrveftfpdfvtegardlisrllkhnpsqrpml
revlehpwitanss