PDB entry 4bvb

View 4bvb on RCSB PDB site
Description: crystal structure of human sirt3 in complex with the inhibitor ex-527 and ADP-ribose
Class: hydrolase
Keywords: hydrolase, nad-dependent deacetylase, inhibitor complex, ADP-ribose
Deposited on 2013-06-25, released 2013-07-17
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-08-07, with a file datestamp of 2013-08-02.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.17313
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NAD-dependent protein deacetylase sirtuin-3, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4bvba_
  • Heterogens: OCZ, AR6, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4bvbA (A:)
gssdkgklslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlpy
peaifelpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidgler
vsgipasklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivffg
eplpqrfllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawhp
rsrdvaqlgdvvhgveslvellgwteemrdlvqretgkldgpdk

    Sequence, based on observed residues (ATOM records): (download) 
    >4bvbA (A:)
klslqdvaeliraracqrvvvmvgagistpsgipdfrspgsglysnlqqydlpypeaife
lpfffhnpkpfftlakelypgnykpnvthyflrllhdkglllrlytqnidglervsgipa
sklveahgtfasatctvcqrpfpgediradvmadrvprcpvctgvvkpdivffgeplpqr
fllhvvdfpmadlllilgtslevepfaslteavrssvprllinrdlvgplawhprsrdva
qlgdvvhgveslvellgwteemrdlvqretgkl