PDB entry 4brx
View 4brx on RCSB PDB site
Description: Focal Adhesion Kinase catalytic domain in complex with a diarylamino- 1,3,5-triazine inhibitor
Class: transferase
Keywords: transferase, kinase inhibitor, ATP-binding, integrin signaling
Deposited on
2013-06-05, released
2013-07-24
The last revision prior to the SCOPe 2.05 freeze date was dated
2013-08-07, with a file datestamp of
2013-08-02.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.1985
AEROSPACI score: 0.43
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Focal adhesion kinase 1
Species: Gallus gallus [TaxId:9031]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d4brxa_ - Heterogens: KGW, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4brxA (A:)
strdyeiqrerielgrcigegqfgdvhqgiymspenpamavaiktcknctsdsvrekflq
ealtmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkfsldlaslilyayql
stalayleskrfvhrdiaarnvlvsatdcvklgdfglsrymedstyykaskgklpikwma
pesinfrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncppt
lyslmtkcwaydpsrrprftelkaqlstileeeklq
Sequence, based on observed residues (ATOM records): (download)
>4brxA (A:)
rdyeiqrerielgrcigegqfgdvhqgiymspenpamavaiktcknctsdsvrekflqea
ltmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkfsldlaslilyayqlst
alayleskrfvhrdiaarnvlvsatdcvklgdfglsrymlpikwmapesinfrrftsasd
vwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydps
rrprftelkaqlstileeek