PDB entry 4bpc

View 4bpc on RCSB PDB site
Description: Structure of the Catalytic Domain of Protein Tyrosine Phosphatase Sigma in the Sulfenic Acid Form
Class: hydrolase
Keywords: hydrolase, proteoglycan, redox regulation
Deposited on 2013-05-24, released 2013-07-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-02-06, with a file datestamp of 2019-02-01.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Receptor-type tyrosine-protein phosphatase S
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13332
      • variant (90)
      • engineered mutation (163)
      • engineered mutation (210)
      • engineered mutation (231)
      • engineered mutation (284)
      • engineered mutation (337)
      • engineered mutation (356)
      • engineered mutation (565)
    Domains in SCOPe 2.08: d4bpca1, d4bpca2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4bpcA (A:)
    mlshppipiadmaehterlkandslklsqeyesidpgqqftwehsnlevnkpknryanvi
    aydhsrvilqpiegimgsdyinanyvdgyrrqnayiatqgplpetfgdfwrmvweqrsat
    ivmmtrleeksrikcdqywpnrgtetygfiqvtlldtielatfavrtfslhkngssekre
    vrqfqftawpdhgvpeyptpflaflrrvktanppdagpivvhcsagvgrtgafividaml
    erikpektvdvyghvtlmrsqrnymvqtedqysfihealleavgagntevparslyayiq
    klaqvepgehvtgmelefkrlanskahtsrfisanlpankfknrlvnimpyestrvalqp
    irgvegsdyinasfidgyrqqkayiatqgplaettedfwrmlwennstivvmltklremg
    rekchqywpaersaryqyfvvdpmaeynmpqyilrefkvtdardgqsrtvrqfqftdwpe
    qgvpksgegfidfigqvhktkeqfgqdgpisvhcsagvgrtgvfitlsivlermryegvv
    difqtvkmlrtqrpamvqtedeyqfayqaaleylgsfdhyat
    

    Sequence, based on observed residues (ATOM records): (download)
    >4bpcA (A:)
    lshppipiadmaehterlkandslklsqeyesidpgqqftwehsnlevnkpknryanvia
    ydhsrvilqpiegimgsdyinanyvdgyrrqnayiatqgplpetfgdfwrmvweqrsati
    vmmtrleeksrikcdqywpnrgtetygfiqvtlldtielatfavrtfslhkngssekrev
    rqfqftawpdhgvpeyptpflaflrrvktanppdagpivvhcsagvgrtgafividamle
    rikpektvdvyghvtlmrsqrnymvqtedqysfihealleavgagntevparslyayiqk
    laqvepgehvtgmelefkrlafisanlpankfknrlvnimpyestrvalqpirgvegsdy
    inasfidgyrqqkayiatqgplaettedfwrmlwennstivvmltklremgrekchqywp
    aersaryqyfvvdpmaeynmpqyilrefkvtdardgqsrtvrqfqftdwpeqgvpksgeg
    fidfigqvhktkeqfgqdgpisvhcsagvgrtgvfitlsivlermryegvvdifqtvkml
    rtqrpamvqtedeyqfayqaaleylgs