PDB entry 4bo6

View 4bo6 on RCSB PDB site
Description: Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 2,3-dihydroindol-1-yl-(2- thiophen-3-yl-1,3-thiazol-4-yl)methanone at 2.8A resolution
Class: oxidoreductase
Keywords: oxidoreductase, rossmann fold, fatty acid biosynthesis
Deposited on 2013-05-18, released 2013-09-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-17, with a file datestamp of 2018-01-12.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54438 (22-268)
      • expression tag (20-21)
    Domains in SCOPe 2.08: d4bo6a1, d4bo6a2
  • Chain 'B':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54438 (22-268)
      • expression tag (17-21)
    Domains in SCOPe 2.08: d4bo6b1, d4bo6b2
  • Chain 'C':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54438 (22-268)
      • expression tag (1-8)
      • expression tag (16-21)
    Domains in SCOPe 2.08: d4bo6c1, d4bo6c2
  • Chain 'D':
    Compound: 3-oxoacyl-[acyl-carrier-protein] reductase FabG
    Species: PSEUDOMONAS AERUGINOSA [TaxId:208964]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O54438 (22-268)
      • expression tag (18-21)
    Domains in SCOPe 2.08: d4bo6d1, d4bo6d2
  • Heterogens: 36P, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4bo6A (A:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo6A (A:)
qsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangvegag
lvldvssdesvaatlehiqqhlgqplivvnnagewfdvvntnlnslyrlskavlrgmtka
rwgriinigsvvgaagqtnyaaakaglegftralarevgsraitvnavapgfidtdmtre
lpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvnggmyms

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4bo6B (B:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo6B (B:)
lyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangve
gaglvldvssdesvaatlehiqqhlgqplivvnnagitdewfdvvntnlnslyrlskavl
rgmtkarwgriinigsvvagqtnyaaakaglegftralarevgsraitvnavapgfidtd
mtrelpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvnggmyms

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4bo6C (C:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo6C (C:)
hhhhhhssnlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekia
etlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdewfdvvntnln
slyrlskavlrgmtkarwgriiniggamgnagqtnyaaakaglegftralarevgsrait
vnavapgfidtdmtrelpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatv
pvnggmyms

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4bo6D (D:)
mhhhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtats
asgaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnll
vrmkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaak
aglegftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeei
akvvgflasdgaayvtgatvpvnggmyms

    Sequence, based on observed residues (ATOM records): (download) 
    >4bo6D (D:)
yfqsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangveg
aglvldvssdesvaatlehiqqhlgqplivvnnagivrmkddewfdvvntnlnslyrlsk
avlrgmtkarwgriinigsvvgamgnagqtnyaaakaglegftralarevgsraitvnav
apgfidpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvnggmyms