PDB entry 4bkz

View 4bkz on RCSB PDB site
Description: Crystal structure of unphosphorylated Maternal Embryonic Leucine zipper Kinase (MELK) in complex with a benzodipyrazole inhibitor
Class: transferase
Keywords: transferase
Deposited on 2013-04-30, released 2013-08-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: maternal embryonic leucine zipper kinase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4bkza_
  • Heterogens: 1WS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4bkzA (A:)
gpkdydellkyyelhetigtggfakvklachiltgemvaikimdkntlgsdlprikteie
alknlrhqhicqlyhvletankifmvleycpggelfdyiisqdrlseeetrvvfrqivsa
vayvhsqgyahrdlkpenllfdeyhklklidfglcakpkgnkdyhlqtccgslayaapel
iqgksylgseadvwsmgillyvlmcgflpfdddnvmalykkimrgkydvpkwlspssill
lqqmlqvdpkkrismknllnhpwimqdynypvewqsknpfihldddcvtelsvhhrnnrq
tmedlislwqydhltatyllllakkargkpvrlrlssfscghhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4bkzA (A:)
kdydellkyyelhetigtgakvklachiltgemvaikimdkntllprikteiealknlrh
qhicqlyhvletankifmvleycpggelfdyiisqdrlseeetrvvfrqivsavayvhsq
gyahrdlkpenllfdeyhklklidfglcaslayaapeliqggseadvwsmgillyvlmcg
flpfdddnvmalykkimrgkydvpkwlspssilllqqmlqvdpkkrismknllnhpwimq
dynypvewqsknpfihldddcvtelsvhhrnnrqtmedlislwqydhltatyllllakka
rgkpvrlrl