PDB entry 4bkj

View 4bkj on RCSB PDB site
Description: Crystal structure of the human DDR1 kinase domain in complex with imatinib
Class: transferase
Keywords: transferase, receptor, rtk, collagen, discoidin domain, receptor tyrosine kinase
Deposited on 2013-04-25, released 2013-05-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: N/A
AEROSPACI score: 0.41 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: epithelial discoidin domain-containing receptor 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q08345 (2-314)
      • expression tag (1)
    Domains in SCOPe 2.08: d4bkja1, d4bkja2
  • Chain 'B':
    Compound: epithelial discoidin domain-containing receptor 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q08345 (2-314)
      • expression tag (1)
    Domains in SCOPe 2.08: d4bkjb1, d4bkjb2
  • Heterogens: STI, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4bkjA (A:)
smprvdfprsrlrfkeklgegqfgevhlcevdspqdlvsldfplnvrkghpllvavkilr
pdatknarndflkevkimsrlkdpniirllgvcvqddplcmitdymengdlnqflsahql
edkaaegapgdgqaaqgptisypmllhvaaqiasgmrylatlnfvhrdlatrnclvgenf
tikiadfgmsrnlyagdyyrvqgravlpirwmawecilmgkfttasdvwafgvtlwevlm
lcraqpfgqltdeqvienageffrdqgrqvylsrppacpqglyelmlrcwsreseqrppf
sqlhrflaedalntv

    Sequence, based on observed residues (ATOM records): (download) 
    >4bkjA (A:)
mprvdfprsrlrfkeklgegqfgevhlcevdspqdlvsldfplnvrkghpllvavkilrp
datknarndflkevkimsrlkdpniirllgvcvqddplcmitdymengdlnqflsahqle
dptisypmllhvaaqiasgmrylatlnfvhrdlatrnclvgenftikiadfgmsrnlyag
dyyravlpirwmawecilmgkfttasdvwafgvtlwevlmlcraqpfgqltdeqvienag
effrdqgrqvylsrppacpqglyelmlrcwsreseqrppfsqlhrflaedalntv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4bkjB (B:)
smprvdfprsrlrfkeklgegqfgevhlcevdspqdlvsldfplnvrkghpllvavkilr
pdatknarndflkevkimsrlkdpniirllgvcvqddplcmitdymengdlnqflsahql
edkaaegapgdgqaaqgptisypmllhvaaqiasgmrylatlnfvhrdlatrnclvgenf
tikiadfgmsrnlyagdyyrvqgravlpirwmawecilmgkfttasdvwafgvtlwevlm
lcraqpfgqltdeqvienageffrdqgrqvylsrppacpqglyelmlrcwsreseqrppf
sqlhrflaedalntv

    Sequence, based on observed residues (ATOM records): (download) 
    >4bkjB (B:)
mprvdfprsrlrfkeklgegqfgevhlcevdspqdlvsldfplnvrkghpllvavkilrp
datknarndflkevkimsrlkdpniirllgvcvqddplcmitdymengdlnqflsahqle
dkgptisypmllhvaaqiasgmrylatlnfvhrdlatrnclvgenftikiadfgmsrnly
agdyyravlpirwmawecilmgkfttasdvwafgvtlwevlmlcraqpfgqltdeqvien
ageffrdqgrqvylsrppacpqglyelmlrcwsreseqrppfsqlhrflaedalntv