PDB entry 4bjx

View 4bjx on RCSB PDB site
Description: n-terminal bromodomain of human brd4 with gsk1324726a (I-bet726)
Class: DNA binding protein
Keywords: DNA binding protein, inhibitor, histone, epigenetic reader
Deposited on 2013-04-20, released 2013-10-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-15, with a file datestamp of 2019-05-10.
Experiment type: XRAY
Resolution: 1.59 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60885 (13-137)
      • expression tag (11-12)
    Domains in SCOPe 2.08: d4bjxa1, d4bjxa2
  • Heterogens: 73B, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4bjxA (A:)
gsshhhhhhsssmnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdav
klnlpdyykiiktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlma
ealeklflqkinelpteeqelvvtipnshkkga

    Sequence, based on observed residues (ATOM records): (download) 
    >4bjxA (A:)
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee