PDB entry 4bf2

View 4bf2 on RCSB PDB site
Description: Crystal Structures of Ask1-inhibitor Complexes
Class: transferase
Keywords: transferase
Deposited on 2013-03-13, released 2013-07-03
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-08-07, with a file datestamp of 2013-08-02.
Experiment type: XRAY
Resolution: 2.11 Å
R-factor: 0.2076
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: mitogen-activated protein kinase kinase kinase 5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q99683
      • engineered mutation (194)
    Domains in SCOPe 2.07: d4bf2a_
  • Chain 'B':
    Compound: mitogen-activated protein kinase kinase kinase 5
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4bf2b_
  • Heterogens: STU, GOL, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4bf2A (A:)
mdykddddkenlyfqgsteegdcesdlleydyeydengdrvvlgkgtygivyagrdlsnq
vriaikeiperdsrysqplheeialhkhlkhknivqylgsfsengfikifmeqvpggsls
allrskwgplkdneqtigfytkqileglkylhdnqivhrdikgdnvlintysgvlkisdf
gtskrlaginpcteeftgtlqymapeiidkgprgygkaadiwslgctiiematgkppfye
lgepqaamfkvgmfkvhpeipesmsaeakafilkcfepdpdkracandllvdeflkvssk
kkktqpklsalsagsneylrsislpvpvlvedts

    Sequence, based on observed residues (ATOM records): (download) 
    >4bf2A (A:)
leydyeydengdrvvlgkgtygivyagrdlsnqvriaikeipeeeialhkhlkhknivqy
lgsfsengfikifmeqvpggslsallrskwgplkdneqtigfytkqileglkylhdnqiv
hrdikgdnvlintysgvlkisdfgtskrlaeeftgtlqymapeiidkgprgygkaadiws
lgctiiematgkppfyelgepqaamfkvgmfkvhpeipesmsaeakafilkcfepdpdkr
acandllvdeflk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4bf2B (B:)
mdykddddkenlyfqgsteegdcesdlleydyeydengdrvvlgkgtygivyagrdlsnq
vriaikeiperdsrysqplheeialhkhlkhknivqylgsfsengfikifmeqvpggsls
allrskwgplkdneqtigfytkqileglkylhdnqivhrdikgdnvlintysgvlkisdf
gtskrlaginpcteeftgtlqymapeiidkgprgygkaadiwslgctiiematgkppfye
lgepqaamfkvgmfkvhpeipesmsaeakafilkcfepdpdkracandllvdeflkvssk
kkktqpklsalsagsneylrsislpvpvlvedts

    Sequence, based on observed residues (ATOM records): (download) 
    >4bf2B (B:)
leydyeydengdrvvlgkgtygivyagrdlsnqvriaikeipereeialhkhlkhknivq
ylgsfsengfikifmeqvpggslsallrskwgplkdneqtigfytkqileglkylhdnqi
vhrdikgdnvlintysgvlkisdfgtskrlatgtlqymapeiidkgprgygkaadiwslg
ctiiematgkppfyelgepqaamfkvgmfkvhpeipesmsaeakafilkcfepdpdkrac
andllvdeflkv