PDB entry 4bel

View 4bel on RCSB PDB site
Description: bace2 xaperone complex
Class: hydrolase/immune system
Keywords: hydrolase-immune system complex, nanobody
Deposited on 2013-03-11, released 2013-05-29
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-06-05, with a file datestamp of 2013-05-31.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.18336
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Beta-secretase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4bela_
  • Chain 'B':
    Compound: Beta-secretase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4belb_
  • Chain 'D':
    Compound: xa4813
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 4BEL (0-End)
    Domains in SCOPe 2.07: d4beld1, d4beld2
  • Chain 'E':
    Compound: xa4813
    Species: LAMA GLAMA [TaxId:9844]
    Database cross-references and differences (RAF-indexed):
    • PDB 4BEL (0-End)
    Domains in SCOPe 2.07: d4bele1, d4bele2
  • Heterogens: CL, B3P, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4belA (A:)
    anflamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdter
    sstyrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwn
    gilglayatlakpsssletffdslvtqanipnvfsmqmcgaglpvagsgtnggslvlggi
    epslykgdiwytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqk
    vfdavveavaraslipefsdgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfrit
    ilpqlyiqpmmgaglnyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspca
    eiagaavseisgpfstedvasncvpa
    

    Sequence, based on observed residues (ATOM records): (download)
    >4belA (A:)
    nflamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdters
    styrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwng
    ilglayatlakpsssletffdslvtqanipnvfsmqmcgagggslvlggiepslykgdiw
    ytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvfdavveava
    rassdgfwtgsqlacwtpwsyfpkisiylrdenssrsfritilpqlyiqpmcyrfgisps
    tnalvigatvmegfyvifdraqkrvgfaaspcaeiagaavseisgpfstedvasncvp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4belB (B:)
    anflamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdter
    sstyrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwn
    gilglayatlakpsssletffdslvtqanipnvfsmqmcgaglpvagsgtnggslvlggi
    epslykgdiwytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqk
    vfdavveavaraslipefsdgfwtgsqlacwtnsetpwsyfpkisiylrdenssrsfrit
    ilpqlyiqpmmgaglnyecyrfgispstnalvigatvmegfyvifdraqkrvgfaaspca
    eiagaavseisgpfstedvasncvpa
    

    Sequence, based on observed residues (ATOM records): (download)
    >4belB (B:)
    nflamvdnlqgdsgrgyylemligtppqklqilvdtgssnfavagtphsyidtyfdters
    styrskgfdvtvkytqgswtgfvgedlvtipkgfntsflvniatifesenfflpgikwng
    ilglayatlakpsssletffdslvtqanipnvfsmqmcgagggslvlggiepslykgdiw
    ytpikeewyyqieilkleiggqslnldcreynadkaivdsgttllrlpqkvfdavveava
    radgfwtgsqlacwtpwsyfpkisiylrdenssrsfritilpqlyiqpmecyrfgispst
    nalvigatvmegfyvifdraqkrvgfaaspcaeiagaavseisgpfstedvasncvp
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4belD (D:)
    qvqlqesggglvqpggslrlscaasgftfssaimtwvrqapgkgrewvstigsdgsitty
    adsvkgrftisrdnarntlylqmnslkpedtavyyctsagrrgpgtqvtvsshhhhhhep
    ea
    

    Sequence, based on observed residues (ATOM records): (download)
    >4belD (D:)
    qvqlqesggglvqpggslrlscaasgftfssaimtwvrqapgkgrewvstigsdgsitty
    adsvkgrftisrdnarntlylqmnslkpedtavyyctsagrrgpgtqvtvss
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >4belE (E:)
    qvqlqesggglvqpggslrlscaasgftfssaimtwvrqapgkgrewvstigsdgsitty
    adsvkgrftisrdnarntlylqmnslkpedtavyyctsagrrgpgtqvtvsshhhhhhep
    ea
    

    Sequence, based on observed residues (ATOM records): (download)
    >4belE (E:)
    qvqlqesggglvqpggslrlscaasgftfssaimtwvrqapgkgrewvstigsdgsitty
    adsvkgrftisrdnarntlylqmnslkpedtavyyctsagrrgpgtqvtvssh