PDB entry 4bbn

View 4bbn on RCSB PDB site
Description: NEDD4 HECT-Ub:Ub complex
Class: ligase/signaling protein
Keywords: ligase-signaling protein complex, ligase, ubiquitination
Deposited on 2012-09-27, released 2013-05-01
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-05-15, with a file datestamp of 2013-05-10.
Experiment type: XRAY
Resolution: 2.51 Å
R-factor: 0.17852
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 ubiquitin-protein ligase NEDD4
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P46934
      • expression tag (3)
      • engineered mutation (111)
      • engineered mutation (113)
      • engineered mutation (262)
    Domains in SCOPe 2.06: d4bbna1, d4bbna2
  • Chain 'C':
    Compound: Polyubiquitin-B
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4bbnc_
  • Chain 'F':
    Compound: Polyubiquitin-B
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0CG53 (0-75)
      • engineered mutation (75)
    Domains in SCOPe 2.06: d4bbnf_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4bbnA (A:)
    gplgsrdykrkyeffrrklkkqndipnkfemklrratvledsyrrimgvkradflkarlw
    iefdgekgldyggvarewffliskemfnpyyglfeysatdnytlqinpnsginpdhlsyf
    kfigrvagmavyhgklldgffirpfykmmlhkpitlhdmesvdseyynslrwilendpte
    ldlrfiideelfgqthqhelknggseivvtnknkkeyiylviqwrfvnriqkqmaafkeg
    ffelipqdlikifdenelellmsglgdvdvndwrehtkykngysanhqviqwfwkavlmm
    dsekrirllqfvtgtsrvpmngfaelygsngpqsftveqwgtpeklprahtcfnrldlpp
    yesfeelwdklqmaientqgfdgvd
    

    Sequence, based on observed residues (ATOM records): (download)
    >4bbnA (A:)
    gsrdykrkyeffrrklkkqndipnkfemklrratvledsyrrimgvkradflkarlwief
    dgekgldyggvarewffliskemfnpyyglfeysatdnytlqinpnsginpdhlsyfkfi
    grvagmavyhgklldgffirpfykmmlhkpitlhdmesvdseyynslrwilendpteldl
    rfiideelfgqthqhelknggseivvtnknkkeyiylviqwrfvnriqkqmaafkegffe
    lipqdlikifdenelellmsglgdvdvndwrehtkykngysanhqviqwfwkavlmmdse
    krirllqfvtgtsrvpmngfaelygsngpqsftveqwgtpeklprahtcfnrldlppyes
    feelwdklqmaientqgf
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4bbnC (C:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgg
    

  • Chain 'F':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4bbnF (F:)
    mqifvktltgktitlevepsdtienvkakiqdkegippdqqrlifagkqledgrtlsdyn
    iqkestlhlvlrlrgc