PDB entry 4b99

View 4b99 on RCSB PDB site
Description: Crystal Structure of MAPK7 (ERK5) with inhibitor
Class: transferase
Keywords: transferase, inhibitor
Deposited on 2012-09-03, released 2012-09-19
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-06-26, with a file datestamp of 2013-06-21.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.22503
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 7
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4b99a_
  • Heterogens: R4L, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4b99A (A:)
smaeplkeedgedgsaeppgpvkaepahtaasvaaknlallkarsfdvtfdvgdeyeiie
tigngaygvvssarrrltgqqvaikkipnafdvvtnakrtlrelkilkhfkhdniiaikd
ilrptvpygefksvyvvldlmesdlhqiihssqpltlehvryflyqllrglkymhsaqvi
hrdlkpsnllvnencelkigdfgmarglctspaehqyfmteyvatrwyrapelmlslhey
tqaidlwsvgcifgemlarrqlfpgknyvhqlqlimmvlgtpspaviqavgaervrayiq
slpprqpvpwetvypgadrqalsllgrmlrfepsarisaaaalrhpflakyhdpddepdc
appfdfafdrealtrerikeaivaeiedfharregirq

    Sequence, based on observed residues (ATOM records): (download) 
    >4b99A (A:)
vtfdvgdeyeiietigngaygvvssarrrltgqqvaikkipnafdvvtnakrtlrelkil
khfkhdniiaikdilrptvpygefksvyvvldlmesdlhqiihssqpltlehvryflyql
lrglkymhsaqvihrdlkpsnllvnencelkigdfgmarglqyfmteyvatrwyrapelm
lslheytqaidlwsvgcifgemlarrqlfpgknyvhqlqlimmvlgtpspaviqrvrayi
qslpprqpvpwetvypgadrqalsllgrmlrfepsarisaaaalrhpflakyhdpddepd
cappfdfafdrealtrerikeaivaeiedfharre