PDB entry 4b8m
View 4b8m on RCSB PDB site
Description: Aurora B kinase in complex with VX-680
Class: cell cycle
Keywords: cell cycle, cancer
Deposited on
2012-08-28, released
2013-07-10
The last revision prior to the SCOPe 2.08 freeze date was dated
2013-07-10, with a file datestamp of
2013-07-05.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.19303
AEROSPACI score: 0.5
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: aurora kinase b-a
Species: Xenopus laevis [TaxId:8355]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4b8ma_ - Chain 'B':
Compound: aurora kinase b-a
Species: Xenopus laevis [TaxId:8355]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4b8mb_ - Chain 'C':
Compound: inner centromere protein a
Species: Xenopus laevis [TaxId:8355]
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: inner centromere protein a
Species: Xenopus laevis [TaxId:8355]
Database cross-references and differences (RAF-indexed):
- Heterogens: VX6, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4b8mA (A:)
atalaempkrkftiddfdigrplgkgkfgnvylarekqnkfimalkvlfksqlekegveh
qlrreieiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatf
meeladalhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldyl
ppemiegkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgs
kdliskllryhppqrlplkgvmehpwvkansrrvlppvyqstqskd
Sequence, based on observed residues (ATOM records): (download)
>4b8mA (A:)
kftiddfdigrplgkgkfgnvylarekqnkfimalkvlfksqlekegvehqlrreieiqs
hlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatfmeeladalhy
cherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldylppemiegkth
dekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgskdliskllry
hppqrlplkgvmehpwvkansrrvlppvyqs
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4b8mB (B:)
atalaempkrkftiddfdigrplgkgkfgnvylarekqnkfimalkvlfksqlekegveh
qlrreieiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatf
meeladalhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldyl
ppemiegkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgs
kdliskllryhppqrlplkgvmehpwvkansrrvlppvyqstqskd
Sequence, based on observed residues (ATOM records): (download)
>4b8mB (B:)
talaempkrkftiddfdigrplgkgkfgnvylarekqnkfimalkvlfksqlekegvehq
lrreieiqshlrhpnilrmynyfhdrkriylmlefaprgelykelqkhgrfdeqrsatfm
eeladalhycherkvihrdikpenllmgykgelkiadfgwsvhapslrrrtmcgtldylp
pemiegkthdekvdlwcagvlcyeflvgmppfdspshtethrrivnvdlkfppflsdgsk
dliskllryhppqrlplkgvmehpwvkansrrvlppvyqs
- Chain 'C':
No sequence available.
- Chain 'D':
No sequence available.