PDB entry 4b2b
View 4b2b on RCSB PDB site
Description: Structure of the factor Xa-like trypsin variant triple-Ala (TGPA) in complex with eglin C
Class: hydrolase/hydrolase inhibitor
Keywords: hydrolase-hydrolase inhibitor complex
Deposited on
2012-07-13, released
2012-08-01
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-05-08, with a file datestamp of
2019-05-03.
Experiment type: XRAY
Resolution: 1.36 Å
R-factor: N/A
AEROSPACI score: 0.56
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: cationic trypsin
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- Uniprot P00760 (0-222)
- engineered mutation (78)
- engineered mutation (80)
- engineered mutation (151-154)
- engineered mutation (194)
- engineered mutation (204)
Domains in SCOPe 2.08: d4b2ba_ - Chain 'B':
Compound: eglin c
Species: Hirudo medicinalis [TaxId:6421]
Database cross-references and differences (RAF-indexed):
- Uniprot P01051 (1-70)
- expression tag (0)
- engineered mutation (45)
Domains in SCOPe 2.08: d4b2bb1, d4b2bb2 - Chain 'C':
Compound: cationic trypsin
Species: Bos taurus [TaxId:9913]
Database cross-references and differences (RAF-indexed):
- Uniprot P00760 (0-222)
- engineered mutation (78)
- engineered mutation (80)
- engineered mutation (151-154)
- engineered mutation (194)
- engineered mutation (204)
Domains in SCOPe 2.08: d4b2bc_ - Chain 'D':
Compound: eglin c
Species: Hirudo medicinalis [TaxId:6421]
Database cross-references and differences (RAF-indexed):
- Uniprot P01051 (1-70)
- expression tag (0)
- engineered mutation (45)
Domains in SCOPe 2.08: d4b2bd1, d4b2bd2 - Heterogens: CA, GOL, EDO, CL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4b2bA (A:)
ivggytcgantvpyqvslnsgyhfcggslinsqwvvsaahcyksgiqvrlgedninvveg
neqfisasksivhpsynsetynndimliklksaaslnsrvasislptscasagtqclisg
wgntkssgtsypdvlkclkapilsdsscksassfiitsnmfcagyleggkdacqgdaggp
vvcsgklqgivswgegcaqknkpgfytkvcnyvswikqtiasn
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>4b2bB (B:)
gtefgselksfpevvgktvdqareyftlhypqydvyflpegspvtkdlrynrvrvfynpg
tnvvnhvphvg
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>4b2bC (C:)
ivggytcgantvpyqvslnsgyhfcggslinsqwvvsaahcyksgiqvrlgedninvveg
neqfisasksivhpsynsetynndimliklksaaslnsrvasislptscasagtqclisg
wgntkssgtsypdvlkclkapilsdsscksassfiitsnmfcagyleggkdacqgdaggp
vvcsgklqgivswgegcaqknkpgfytkvcnyvswikqtiasn
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>4b2bD (D:)
gtefgselksfpevvgktvdqareyftlhypqydvyflpegspvtkdlrynrvrvfynpg
tnvvnhvphvg