SCOPe 2.05: Structural Classification of Proteins

PDB entry 4b0j

View 4b0j on RCSB PDB site
Description: Crystal Structure of 3-hydroxydecanoyl-Acyl Carrier Protein Dehydratase (FabA) from Pseudomonas aeruginosa in complex with 5-(2- thienyl)-3-isoxazolyl methanol
Class: lyase
Keywords: lyase, fatty acid biosynthesis, bacterial virulence, drug discovery
Deposited on 2012-07-02, released 2012-11-28
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-09-04, with a file datestamp of 2013-08-30.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: 0.23456
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0ja_
Chain 'B':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jb_
Chain 'C':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jc_
Chain 'D':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jd_
Chain 'E':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0je_
Chain 'F':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jf_
Chain 'G':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jg_
Chain 'H':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jh_
Chain 'I':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0ji_
Chain 'J':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jj_
Chain 'K':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jk_
Chain 'L':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jl_
Chain 'M':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jm_
Chain 'N':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jn_
Chain 'O':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jo_
Chain 'P':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jp_
Chain 'Q':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jq_
Chain 'R':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jr_
Chain 'S':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0js_
Chain 'T':
Compound: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase
Species: Pseudomonas aeruginosa [TaxId:208964]
Database cross-references and differences (RAF-indexed):
- Uniprot O33877 (Start-170)
Domains in SCOPe 2.05: d4b0jt_
Heterogens: 3MQ, HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>4b0jA (A:)
mtkqhaftredllrcsrgelfgpgnaqlpapnmlmidrivhisdvggkygkgelvaeldi
npdlwffachfegdpvmpgclgldamwqlvgfylgwqgnpgrgralgsgevkffgqvlpt
akkvtynihikrtinrslvlaiadgtvsvdgreiysaeglrvglftstdsf