PDB entry 4azm

View 4azm on RCSB PDB site
Description: Human epidermal fatty acid-binding protein (FABP5) in complex with the inhibitor BMS-309413
Class: lipid binding protein
Keywords: lipid binding protein, lipid carrier protein, endocannabinoid, beta-barrel, beta-clamshell, domain swapping
Deposited on 2012-06-26, released 2013-08-07
The last revision prior to the SCOPe 2.06 freeze date was dated 2014-02-26, with a file datestamp of 2014-02-21.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: 0.20739
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: fatty acid-binding protein, epidermal
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q01469 (3-End)
      • expression tag (2)
    Domains in SCOPe 2.06: d4azma1, d4azma2
  • Chain 'B':
    Compound: fatty acid-binding protein, epidermal
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4azmb_
  • Heterogens: T4B, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4azmA (A:)
gshmatvqqlegrwrlvdskgfdeymkelgvgialrkmgamakpdciitcdgknltikte
stlkttqfsctlgekfeettadgrktqtvcnftdgalvqhqewdgkestitrklkdgklv
vecvmnnvtctriyekve

    Sequence, based on observed residues (ATOM records): (download) 
    >4azmA (A:)
hmatvqqlegrwrlvdskgfdeymkelgvgialrkmgamakpdciitcdgknltiktest
lkttqfsctlgekfeettadgrktqtvcnftdgalvqhqewdgkestitrklkdgklvve
cvmnnvtctriyekv

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4azmB (B:)
gshmatvqqlegrwrlvdskgfdeymkelgvgialrkmgamakpdciitcdgknltikte
stlkttqfsctlgekfeettadgrktqtvcnftdgalvqhqewdgkestitrklkdgklv
vecvmnnvtctriyekve

    Sequence, based on observed residues (ATOM records): (download) 
    >4azmB (B:)
atvqqlegrwrlvdskgfdeymkelgvgialrkmgamakpdciitcdgknltiktestlk
ttqfsctlgekfeettadgrktqtvcnftdgalvqhqewdgkestitrklkdgklvvecv
mnnvtctriyekve