PDB entry 4ax4

View 4ax4 on RCSB PDB site
Description: prolyl oligopeptidase from porcine brain, h680a mutant
Class: hydrolase
Keywords: hydrolase, amnesia, alpha/beta-hydrolase, beta-propeller, serine protease
Deposited on 2012-06-08, released 2012-09-26
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-12-19, with a file datestamp of 2012-12-14.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.16368
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: prolyl oligopeptidase
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23687 (0-709)
      • engineered mutation (679)
    Domains in SCOPe 2.06: d4ax4a1, d4ax4a2
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ax4A (A:)
mlsfqypdvyrdetaiqdyhghkvcdpyawledpdseqtkafveaqnkitvpfleqcpir
glykermtelydypkyschfkkgkryfyfyntglqnqrvlyvqdslegearvfldpnils
ddgtvalrgyafsedgeyfayglsasgsdwvtikfmkvdgakelpdvlervkfscmawth
dgkgmfynaypqqdgksdgtetstnlhqklyyhvlgtdqsedilcaefpdepkwmggael
sddgryvllsiregcdpvnrlwycdlqqesngitgilkwvklidnfegeydyvtnegtvf
tfktnrhspnyrlinidftdpeeskwkvlvpehekdvlewvacvrsnflvlcylhdvknt
lqlhdlatgallkifplevgsvvgysgqkkdteifyqftsflspgiiyhcdltkeelepr
vfrevtvkgidasdyqtvqifypskdgtkipmfivhkkgikldgshpaflygyggfnisi
tpnysvsrlifvrhmggvlavanirgggeygetwhkggilankqncfddfqcaaeylike
gytspkrltinggsnggllvatcanqrpdlfgcviaqvgvmdmlkfhkytighawttdyg
csdskqhfewlikysplhnvklpeaddiqypsmllltadhddrvvplhslkfiatlqyiv
grsrkqnnpllihvdtkagagagkptakvieevsdmfafiarclnidwip

    Sequence, based on observed residues (ATOM records): (download) 
    >4ax4A (A:)
mlsfqypdvyrdetaiqdyhghkvcdpyawledpdseqtkafveaqnkitvpfleqcpir
glykermtelydypkyschfkkgkryfyfyntglqnqrvlyvqdslegearvfldpnils
ddgtvalrgyafsedgeyfayglsasgsdwvtikfmkvdgakelpdvlervkfscmawth
dgkgmfynayptstnlhqklyyhvlgtdqsedilcaefpdepkwmggaelsddgryvlls
iregcdpvnrlwycdlqqesngitgilkwvklidnfegeydyvtnegtvftfktnrhspn
yrlinidftdpeeskwkvlvpehekdvlewvacvrsnflvlcylhdvkntlqlhdlatga
llkifplevgsvvgysgqkkdteifyqftsflspgiiyhcdltkeeleprvfrevtvkgi
dasdyqtvqifypskdgtkipmfivhkkgikldgshpaflygyggfnisitpnysvsrli
fvrhmggvlavanirgggeygetwhkggilankqncfddfqcaaeylikegytspkrlti
nggsnggllvatcanqrpdlfgcviaqvgvmdmlkfhkytighawttdygcsdskqhfew
likysplhnvklpeaddiqypsmllltadhddrvvplhslkfiatlqyivgrsrkqnnpl
lihvdtkagagagkptakvieevsdmfafiarclnidwip