PDB entry 4awz

View 4awz on RCSB PDB site
Description: Crystal Structure of the Mobile Metallo-beta-Lactamase AIM-1 from Pseudomonas aeruginosa: Insights into Antibiotic Binding and the role of Gln157
Class: hydrolase
Keywords: hydrolase, antibiotic resistance, acquired b3, drug binding site,
Deposited on 2012-06-06, released 2012-06-20
The last revision prior to the SCOPe 2.06 freeze date was dated 2012-08-15, with a file datestamp of 2012-08-10.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.14049
AEROSPACI score: 0.56 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: metallo-beta-lactamase aim-1
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4awza_
  • Chain 'B':
    Compound: metallo-beta-lactamase aim-1
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4awzb_
  • Chain 'C':
    Compound: metallo-beta-lactamase aim-1
    Species: Pseudomonas aeruginosa [TaxId:287]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d4awzc_
  • Heterogens: CA, MG, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4awzA (A:)
mkrrftllgsvvalalsstalasdapasrgcaddagwndpamplkvygntwyvgtcgisa
llvtsdaghilvdaatpqagpqilaniralgfrpedvraivfshehfdhagslaelqkat
gapvyarapaidtlkrglpdrtdpqfevaepvapvanivtladdgvvsvgplaltavasp
ghtpggtswtwrscegddcrqmvyadsltaisddvfrysddaahpgylaafrntlarvaa
ldcdilvtphpsasglwnrigpraaaplmdttacrryaqgarqrlekrlaeeaatspssg
arp

    Sequence, based on observed residues (ATOM records): (download) 
    >4awzA (A:)
asrgcaddagwndpamplkvygntwyvgtcgisallvtsdaghilvdaatpqagpqilan
iralgfrpedvraivfshehfdhagslaelqkatgapvyarapaidtlkrglpdrtdpqf
evaepvapvanivtladdgvvsvgplaltavaspghtpggtswtwrscegddcrqmvyad
sltaisddvfrysddaahpgylaafrntlarvaaldcdilvtphpsasglwnrigpraaa
plmdttacrryaqgarqrlekrlaeeaat

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4awzB (B:)
mkrrftllgsvvalalsstalasdapasrgcaddagwndpamplkvygntwyvgtcgisa
llvtsdaghilvdaatpqagpqilaniralgfrpedvraivfshehfdhagslaelqkat
gapvyarapaidtlkrglpdrtdpqfevaepvapvanivtladdgvvsvgplaltavasp
ghtpggtswtwrscegddcrqmvyadsltaisddvfrysddaahpgylaafrntlarvaa
ldcdilvtphpsasglwnrigpraaaplmdttacrryaqgarqrlekrlaeeaatspssg
arp

    Sequence, based on observed residues (ATOM records): (download) 
    >4awzB (B:)
rgcaddagwndpamplkvygntwyvgtcgisallvtsdaghilvdaatpqagpqilanir
algfrpedvraivfshehfdhagslaelqkatgapvyarapaidtlkrglpdrtdpqfev
aepvapvanivtladdgvvsvgplaltavaspghtpggtswtwrscegddcrqmvyadsl
taisddvfrysddaahpgylaafrntlarvaaldcdilvtphpsasglwnrigpraaapl
mdttacrryaqgarqrlekrlaeeaat

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4awzC (C:)
mkrrftllgsvvalalsstalasdapasrgcaddagwndpamplkvygntwyvgtcgisa
llvtsdaghilvdaatpqagpqilaniralgfrpedvraivfshehfdhagslaelqkat
gapvyarapaidtlkrglpdrtdpqfevaepvapvanivtladdgvvsvgplaltavasp
ghtpggtswtwrscegddcrqmvyadsltaisddvfrysddaahpgylaafrntlarvaa
ldcdilvtphpsasglwnrigpraaaplmdttacrryaqgarqrlekrlaeeaatspssg
arp

    Sequence, based on observed residues (ATOM records): (download) 
    >4awzC (C:)
asrgcaddagwndpamplkvygntwyvgtcgisallvtsdaghilvdaatpqagpqilan
iralgfrpedvraivfshehfdhagslaelqkatgapvyarapaidtlkrglpdrtdpqf
evaepvapvanivtladdgvvsvgplaltavaspghtpggtswtwrscegddcrqmvyad
sltaisddvfrysddaahpgylaafrntlarvaaldcdilvtphpsasglwnrigpraaa
plmdttacrryaqgarqrlekrlaeeaat