PDB entry 4awo
View 4awo on RCSB PDB site
Description: Complex of HSP90 ATPase domain with tropane derived inhibitors
Class: chaperone
Keywords: chaperone
Deposited on
2012-06-05, released
2012-08-29
The last revision prior to the SCOPe 2.08 freeze date was dated
2012-08-29, with a file datestamp of
2012-08-24.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.21504
AEROSPACI score: 0.52
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Heat shock protein HSP 90-alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4awoa_ - Chain 'B':
Compound: Heat shock protein HSP 90-alpha
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d4awob_ - Heterogens: 99B, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4awoA (A:)
gsdqpmeeeevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltd
pskldsgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqaga
dismigqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkv
ilhlkedqteyleerrikeivkkhsqfigypitlfvekerdkevsddeae
Sequence, based on observed residues (ATOM records): (download)
>4awoA (A:)
vetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgkel
hinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqdismigqfgvgfy
saylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqteyle
errikeivkkhsqfigypitlfvek
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4awoB (B:)
gsdqpmeeeevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltd
pskldsgkelhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqaga
dismigqfgvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkv
ilhlkedqteyleerrikeivkkhsqfigypitlfvekerdkevsddeae
Sequence, based on observed residues (ATOM records): (download)
>4awoB (B:)
vetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryesltdpskldsgkel
hinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqdismigqfgvgfy
saylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqteyle
errikeivkkhsqfigypitlfve