PDB entry 4awi

View 4awi on RCSB PDB site
Description: Human Jnk1alpha kinase with 4-phenyl-7-azaindole IKK2 inhibitor.
Class: transferase
Keywords: transferase
Deposited on 2012-06-03, released 2013-05-01
The last revision prior to the SCOPe 2.02 freeze date was dated 2013-05-01, with a file datestamp of 2013-04-26.
Experiment type: XRAY
Resolution: 1.91 Å
R-factor: 0.18769
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 8
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.02: d4awia_
  • Heterogens: AQ2, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4awiA (A:)
gplgsmsrskrdnnfysveigdstftvlkryqnlkpigsgaqgivcaaydailernvaik
klsrpfqnqthakrayrelvlmkcvnhkniigllnvftpqksleefqdvyivmelmdanl
cqviqmeldhermsyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglart
agtsfmmtpyvvtryyrapevilgmgykenvdlwsvgcimgemvchkilfpgrdyidqwn
kvieqlgtpcpefmkklqptvrtyvenrpkyagysfeklfpdvlfpadsehnklkasqar
dllskmlvidaskrisvdealqhpyinvwydpseaeapppkipdkqlderehtieewkel
iykevmdle

    Sequence, based on observed residues (ATOM records): (download) 
    >4awiA (A:)
nnfysveigdstftvlkryqnlkpigsgaqgivcaaydailernvaikklsrpfqnqtha
krayrelvlmkcvnhkniigllnvftpqksleefqdvyivmelmdanlcqviqmeldher
msyllyqmlcgikhlhsagiihrdlkpsnivvksdctlkildfglasfmmtpyvvtryyr
apevilgmgykenvdlwsvgcimgemvchkilfpgrdyidqwnkvieqlgtpcpefmkkl
qptvrtyvenrpkyagysfeklfpdvlfpadsehnklkasqardllskmlvidaskrisv
dealqhpyinvwydpseaeapppkipdkqlderehtieewkeliykevmdle