PDB entry 4asu

View 4asu on RCSB PDB site
Description: F1-ATPase in which all three catalytic sites contain bound nucleotide, with magnesium ion released in the Empty site
Class: hydrolase
Keywords: hydrolase
Deposited on 2012-05-03, released 2012-06-27
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-07-25, with a file datestamp of 2012-07-20.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.24711
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP synthase subunit alpha, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19483 (Start-509)
      • see remark 999 (480)
    Domains in SCOPe 2.05: d4asua1, d4asua2, d4asua3
  • Chain 'B':
    Compound: ATP synthase subunit alpha, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19483 (Start-509)
      • see remark 999 (480)
    Domains in SCOPe 2.05: d4asub1, d4asub2, d4asub3
  • Chain 'C':
    Compound: ATP synthase subunit alpha, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19483 (Start-509)
      • see remark 999 (480)
    Domains in SCOPe 2.05: d4asuc1, d4asuc2, d4asuc3
  • Chain 'D':
    Compound: ATP synthase subunit beta, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4asud1, d4asud2, d4asud3
  • Chain 'E':
    Compound: ATP synthase subunit beta, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4asue1, d4asue2, d4asue3
  • Chain 'F':
    Compound: ATP synthase subunit beta, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4asuf1, d4asuf2, d4asuf3
  • Chain 'G':
    Compound: ATP synthase subunit gamma, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4asug_
  • Chain 'H':
    Compound: ATP synthase subunit delta, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: ATP synthase subunit epsilon, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4asui_
  • Heterogens: ADP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4asuA (A:)
    qktgtaevssileerilgadtsvdleetgrvlsigdgiarvhglrnvqaeemvefssglk
    gmslnlepdnvgvvvfgndklikegdivkrtgaivdvpvgeellgrvvdalgnaidgkgp
    igskarrrvglkapgiiprisvrepmqtgikavdslvpigrgqreliigdrqtgktsiai
    dtiinqkrfndgtdekkklyciyvaigqkrstvaqlvkrltdadamkytivvsatasdaa
    plqylapysgcsmgeyfrdngkhaliiyddlskqavayrqmslllrrppgreaypgdvfy
    lhsrlleraakmndafgggsltalpvietqagdvsayiptnvisitdgqifletelfykg
    irpainvglsvsrvgsaaqtramkqvagtmklelaqyrevaafaqfgsdldaatqqllsr
    gvrltellkqgqyspmaieeqvaviyagvrgyldklepskitkfenaflshvisqhqall
    gkirtdgkiseesdaklkeivtnflagfea
    

    Sequence, based on observed residues (ATOM records): (download)
    >4asuA (A:)
    dleetgrvlsigdgiarvhglrnvqaeemvefssglkgmslnlepdnvgvvvfgndklik
    egdivkrtgaivdvpvgeellgrvvdalgnaidgkgpigskarrrvglkapgiiprisvr
    epmqtgikavdslvpigrgqreliigdrqtgktsiaidtiinqkrfndgtdekkklyciy
    vaigqkrstvaqlvkrltdadamkytivvsatasdaaplqylapysgcsmgeyfrdngkh
    aliiyddlskqavayrqmslllrrppgreaypgdvfylhsrlleraakmndafgggslta
    lpvietqagdvsayiptnvisitdgqifletelfykgirpainvglsvsrvgsaaqtram
    kqvagtmklelaqyrevaafaqfgsdldaatqqllsrgvrltellkqgqyspmaieeqva
    viyagvrgyldklepskitkfenaflshvisqhqallgkirtdgkiseesdaklkeivtn
    flagfea
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4asuB (B:)
    qktgtaevssileerilgadtsvdleetgrvlsigdgiarvhglrnvqaeemvefssglk
    gmslnlepdnvgvvvfgndklikegdivkrtgaivdvpvgeellgrvvdalgnaidgkgp
    igskarrrvglkapgiiprisvrepmqtgikavdslvpigrgqreliigdrqtgktsiai
    dtiinqkrfndgtdekkklyciyvaigqkrstvaqlvkrltdadamkytivvsatasdaa
    plqylapysgcsmgeyfrdngkhaliiyddlskqavayrqmslllrrppgreaypgdvfy
    lhsrlleraakmndafgggsltalpvietqagdvsayiptnvisitdgqifletelfykg
    irpainvglsvsrvgsaaqtramkqvagtmklelaqyrevaafaqfgsdldaatqqllsr
    gvrltellkqgqyspmaieeqvaviyagvrgyldklepskitkfenaflshvisqhqall
    gkirtdgkiseesdaklkeivtnflagfea
    

    Sequence, based on observed residues (ATOM records): (download)
    >4asuB (B:)
    vdleetgrvlsigdgiarvhglrnvqaeemvefssglkgmslnlepdnvgvvvfgndkli
    kegdivkrtgaivdvpvgeellgrvvdalgnaidgkgpigskarrrvglkapgiiprisv
    repmqtgikavdslvpigrgqreliigdrqtgktsiaidtiinqkrfndgtdekkklyci
    yvaigqkrstvaqlvkrltdadamkytivvsatasdaaplqylapysgcsmgeyfrdngk
    haliiyddlskqavayrqmslllrrppgreaypgdvfylhsrlleraakmndafgggslt
    alpvietqagdvsayiptnvisitdgqifletelfykgirpainvglsvsrvgsaaqtra
    mkqvagtmklelaqyrevaldaatqqllsrgvrltellkqgqyspmaieeqvaviyagvr
    gyldklepskitkfenaflshvisqhqallgkirtdgkiseesdaklkeivtnflagfea
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4asuC (C:)
    qktgtaevssileerilgadtsvdleetgrvlsigdgiarvhglrnvqaeemvefssglk
    gmslnlepdnvgvvvfgndklikegdivkrtgaivdvpvgeellgrvvdalgnaidgkgp
    igskarrrvglkapgiiprisvrepmqtgikavdslvpigrgqreliigdrqtgktsiai
    dtiinqkrfndgtdekkklyciyvaigqkrstvaqlvkrltdadamkytivvsatasdaa
    plqylapysgcsmgeyfrdngkhaliiyddlskqavayrqmslllrrppgreaypgdvfy
    lhsrlleraakmndafgggsltalpvietqagdvsayiptnvisitdgqifletelfykg
    irpainvglsvsrvgsaaqtramkqvagtmklelaqyrevaafaqfgsdldaatqqllsr
    gvrltellkqgqyspmaieeqvaviyagvrgyldklepskitkfenaflshvisqhqall
    gkirtdgkiseesdaklkeivtnflagfea
    

    Sequence, based on observed residues (ATOM records): (download)
    >4asuC (C:)
    dleetgrvlsigdgiarvhglrnvqaeemvefssglkgmslnlepdnvgvvvfgndklik
    egdivkrtgaivdvpvgeellgrvvdalgnaidgkgpigskarrrvglkapgiiprisvr
    epmqtgikavdslvpigrgqreliigdrqtgktsiaidtiinqkrfndgtdekkklyciy
    vaigqkrstvaqlvkrltdadamkytivvsatasdaaplqylapysgcsmgeyfrdngkh
    aliiyddlskqavayrqmslllrrppgreaypgdvfylhsrlleraakmndafgggslta
    lpvietqagdvsayiptnvisitdgqifletelfykgirpainvglsvsrvgsaaqtram
    kqvagtmklelaqyrevaafagsdldaatqqllsrgvrltellkqgqyspmaieeqvavi
    yagvrgyldklepskitkfenaflshvisqhqallgkirtdgkiseesdaklkeivtnfl
    agfea
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >4asuD (D:)
    qaspspkagattgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlgestv
    rtiamdgteglvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaaiha
    eapefvemsveqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvakahg
    gysvfagvgertregndlyhemiesgvinlkdatskvalvygqmneppgararvaltglt
    vaeyfrdqegqdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeritt
    tkkgsitsvqaiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsrim
    dpnivgsehydvargvqkilqdykslqdiiailgmdelseedkltvsrarkiqrflsqpf
    qvaevftghlgklvplketikgfqqilageydhlpeqafymvgpieeavakadklaeehs
    

    Sequence, based on observed residues (ATOM records): (download)
    >4asuD (D:)
    ttgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlgestvrtiamdgteg
    lvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaaihaeapefvemsv
    eqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvakahggysvfagvge
    rtregndlyhemiesgvinlkdatskvalvygqmneppgararvaltgltvaeyfrdqeg
    qdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeritttkkgsitsvq
    aiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsrimdpnivgsehy
    dvargvqkilqdykslqdiiailgmdelseedkltvsrarkiqrflsqpfqvaevftghl
    gklvplketikgfqqilageydhlpeqafymvgpieeavakadklae
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >4asuE (E:)
    qaspspkagattgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlgestv
    rtiamdgteglvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaaiha
    eapefvemsveqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvakahg
    gysvfagvgertregndlyhemiesgvinlkdatskvalvygqmneppgararvaltglt
    vaeyfrdqegqdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeritt
    tkkgsitsvqaiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsrim
    dpnivgsehydvargvqkilqdykslqdiiailgmdelseedkltvsrarkiqrflsqpf
    qvaevftghlgklvplketikgfqqilageydhlpeqafymvgpieeavakadklaeehs
    

    Sequence, based on observed residues (ATOM records): (download)
    >4asuE (E:)
    ttgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlgestvrtiamdgteg
    lvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaaihaeapefvemsv
    eqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvakahggysvfagvge
    rtregndlyhemiesgvinlkdatskvalvygqmneppgararvaltgltvaeyfrdqeg
    qdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeritttkkgsitsvq
    aiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsrimdpnivgsehy
    dvargvqkilqdykslqdilseedkltvsrarkiqrflsqpfqvaevftghlgklvplke
    tikgfqqilageydhlpeqafymvgpieeavakadkla
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >4asuF (F:)
    qaspspkagattgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlgestv
    rtiamdgteglvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaaiha
    eapefvemsveqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvakahg
    gysvfagvgertregndlyhemiesgvinlkdatskvalvygqmneppgararvaltglt
    vaeyfrdqegqdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeritt
    tkkgsitsvqaiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsrim
    dpnivgsehydvargvqkilqdykslqdiiailgmdelseedkltvsrarkiqrflsqpf
    qvaevftghlgklvplketikgfqqilageydhlpeqafymvgpieeavakadklaeehs
    

    Sequence, based on observed residues (ATOM records): (download)
    >4asuF (F:)
    ttgrivavigavvdvqfdeglppilnalevqgretrlvlevaqhlgestvrtiamdgteg
    lvrgqkvldsgapiripvgpetlgrimnvigepidergpiktkqfaaihaeapefvemsv
    eqeilvtgikvvdllapyakggkiglfggagvgktvlimelinnvakahggysvfagvge
    rtregndlyhemiesgvinlkdatskvalvygqmneppgararvaltgltvaeyfrdqeg
    qdvllfidnifrftqagsevsallgripsavgyqptlatdmgtmqeritttkkgsitsvq
    aiyvpaddltdpapattfahldattvlsraiaelgiypavdpldstsrimdpnivgsehy
    dvargvqkilqdykslqdiiailgmdelseedkltvsrarkiqrflsqpfqvaevftghl
    gklvplketikgfqqilageydhlpeqafymvgpieeavakadkla
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >4asuG (G:)
    atlkditrrlksikniqkitksmkmvaaakyaraerelkparvygvgslalyekadiktp
    edkkkhliigvssdrglcgaihssvakqmkseaanlaaagkevkiigvgdkirsilhrth
    sdqflvtfkevgrrpptfgdasvialellnsgyefdegsiifnrfrsvisykteekpifs
    ldtissaesmsiyddidadvlrnyqeyslaniiyyslkesttseqsarmtamdnasknas
    emidkltltfnrtrqavitkelieiisgaaald
    

    Sequence, based on observed residues (ATOM records): (download)
    >4asuG (G:)
    atlkditrrlksikniqkitksmkmvaaakyaraerelkparvygvgliigvssdrglcg
    aihssvaiigvgdkirsiltfkevgrrpptfgdasvialelsiifnrfrsvisykteysl
    aniiyyslkesttseqsarmtamdnasknasemidkltltfnrtrqavitkelieiisga
    a
    

  • Chain 'H':
    No sequence available.

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >4asuI (I:)
    vaywrqaglsyirysqicakavrdalktefkanamktsgstikivkvkke
    

    Sequence, based on observed residues (ATOM records): (download)
    >4asuI (I:)
    syirysqicakavrdatikivkv