PDB entry 4aqh

View 4aqh on RCSB PDB site
Description: Plasminogen activator inhibitor type-1 in complex with the inhibitor AZ3976
Class: hydolase inhibitor
Keywords: hydolase inhibitor, latent form
Deposited on 2012-04-17, released 2012-11-28
The last revision prior to the SCOPe 2.07 freeze date was dated 2013-01-30, with a file datestamp of 2013-01-25.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.15867
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Plasminogen activator inhibitor 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05121 (4-382)
      • expression tag (1-3)
    Domains in SCOPe 2.07: d4aqha1, d4aqha2
  • Chain 'B':
    Compound: Plasminogen activator inhibitor 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05121 (4-382)
      • expression tag (0-3)
    Domains in SCOPe 2.07: d4aqhb1, d4aqhb2
  • Chain 'C':
    Compound: Plasminogen activator inhibitor 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P05121 (4-382)
      • expression tag (1-3)
    Domains in SCOPe 2.07: d4aqhc1, d4aqhc2
  • Heterogens: TB7, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4aqhA (A:)
    gshmvhhppsyvahlasdfgvrvfqqvaqaskdrnvvfspygvasvlamlqlttggetqq
    qiqaamgfkiddkgmapalrhlykelmgpwnkdeisttdaifvqrdlklvqgfmphffrl
    frstvkqvdfseverarfiindwvkthtkgmisnllgkgavdqltrlvlvnalyfngqwk
    tpfpdssthrrlfhksdgstvsvpmmaqtnkfnytefttpdghyydilelpyhgdtlsmf
    iaapyekevplsaltnilsaqlishwkgnmtrlprllvlpkfsletevdlrkplenlgmt
    dmfrqfqadftslsdqeplhvaqalqkvkievnesgtvassstavivsarmapeeiimdr
    pflfvvrhnptgtvlfmgqvmep
    

    Sequence, based on observed residues (ATOM records): (download)
    >4aqhA (A:)
    shmvhhppsyvahlasdfgvrvfqqvaqaskdrnvvfspygvasvlamlqlttggetqqq
    iqaamgfkiddkgmapalrhlykelmgpwnkdeisttdaifvqrdlklvqgfmphffrlf
    rstvkqvdfseverarfiindwvkthtkgmisnllgkgavdqltrlvlvnalyfngqwkt
    pfpdssthrrlfhksdgstvsvpmmaqtnkfnytefttpdghyydilelpyhgdtlsmfi
    aapyekevplsaltnilsaqlishwkgnmtrlprllvlpkfsletevdlrkplenlgmtd
    mfrqfqadftslsdqeplhvaqalqkvkievnesgtvassstavivsarmapeeiimdrp
    flfvvrhnptgtvlfmgqvmep
    

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download)
    >4aqhB (B:)
    gshmvhhppsyvahlasdfgvrvfqqvaqaskdrnvvfspygvasvlamlqlttggetqq
    qiqaamgfkiddkgmapalrhlykelmgpwnkdeisttdaifvqrdlklvqgfmphffrl
    frstvkqvdfseverarfiindwvkthtkgmisnllgkgavdqltrlvlvnalyfngqwk
    tpfpdssthrrlfhksdgstvsvpmmaqtnkfnytefttpdghyydilelpyhgdtlsmf
    iaapyekevplsaltnilsaqlishwkgnmtrlprllvlpkfsletevdlrkplenlgmt
    dmfrqfqadftslsdqeplhvaqalqkvkievnesgtvassstavivsarmapeeiimdr
    pflfvvrhnptgtvlfmgqvmep
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >4aqhC (C:)
    gshmvhhppsyvahlasdfgvrvfqqvaqaskdrnvvfspygvasvlamlqlttggetqq
    qiqaamgfkiddkgmapalrhlykelmgpwnkdeisttdaifvqrdlklvqgfmphffrl
    frstvkqvdfseverarfiindwvkthtkgmisnllgkgavdqltrlvlvnalyfngqwk
    tpfpdssthrrlfhksdgstvsvpmmaqtnkfnytefttpdghyydilelpyhgdtlsmf
    iaapyekevplsaltnilsaqlishwkgnmtrlprllvlpkfsletevdlrkplenlgmt
    dmfrqfqadftslsdqeplhvaqalqkvkievnesgtvassstavivsarmapeeiimdr
    pflfvvrhnptgtvlfmgqvmep
    

    Sequence, based on observed residues (ATOM records): (download)
    >4aqhC (C:)
    shmvhhppsyvahlasdfgvrvfqqvaqaskdrnvvfspygvasvlamlqlttggetqqq
    iqaamgfkiddkgmapalrhlykelmgpwnkdeisttdaifvqrdlklvqgfmphffrlf
    rstvkqvdfseverarfiindwvkthtkgmisnllgkgavdqltrlvlvnalyfngqwkt
    pfpdssthrrlfhksdgstvsvpmmaqtnkfnytefttpdghyydilelpyhgdtlsmfi
    aapyekevplsaltnilsaqlishwkgnmtrlprllvlpkfsletevdlrkplenlgmtd
    mfrqfqadftslsdqeplhvaqalqkvkievnesgtvassstavivsarmapeeiimdrp
    flfvvrhnptgtvlfmgqvmep