PDB entry 4ap2

View 4ap2 on RCSB PDB site
Description: Crystal structure of the human KLHL11-Cul3 complex at 2.8A resolution
Class: cell cycle
Keywords: ubiquitination, e3 ligase, cell cycle
Deposited on 2012-03-30, released 2012-05-09
The last revision prior to the SCOPe 2.05 freeze date was dated 2013-03-27, with a file datestamp of 2013-03-22.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.2059
AEROSPACI score: 0.28 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Kelch-like protein 11
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: cullin-3
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q13618
      • engineered mutation (341)
      • engineered mutation (345)
    Domains in SCOPe 2.05: d4ap2b_
  • Heterogens: EDO, IOD, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ap2B (B:)
msnlskgtgsrkdtkmrirafpmtmdekyvnsiwdllknaiqeiqrknnsglsfeelyrn
aytmvlhkhgeklytglrevvtehlinkvredvlnslnnnflqtlnqawndhqtamvmir
dilmymdrvyvqqnnvenvynlgliifrdqvvrygcirdhlrqtlldmiarerkgevvdr
gairnacqmlmilglegrsvyeedfeapflemsaeffqmesqkflaensasvyikkvear
ineeiervmhcldksteepivkvvereliskhmktivemensglvhmlkngktedlgcmy
klfsrvpnglktmcecmssylreqgkalvseegegknpvdyrqglddlksrfdrfllesf
nndrlfkqtiagdfeyflnlnsrspeylaenlyfqshhhhhhdykddddk

    Sequence, based on observed residues (ATOM records): (download) 
    >4ap2B (B:)
rirafpmtmdekyvnsiwdllknaiqeiqrknnsglsfeelyrnaytmvlhkhgeklytg
lrevvtehlinkvredvlnslnnnflqtlnqawndhqtamvmirdilmymdrvyvqqnnv
envynlgliifrdqvvrygcirdhlrqtlldmiarerkgevvdrgairnacqmlmilgle
grsvyeedfeapflemsaeffqmesqkflaensasvyikkvearineeiervmhcldkst
eepivkvvereliskhmktivemensglvhmlkngktedlgcmyklfsrvpnglktmcec
mssylreqgkalvsepvdyrqglddlksrfdrfllesfnndrlfkqtiagdfeyflnln