PDB entry 4aoj

View 4aoj on RCSB PDB site
Description: Human TrkA in complex with the inhibitor AZ-23
Class: transferase
Keywords: transferase, inhibitor
Deposited on 2012-03-28, released 2012-08-15
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-06-18, with a file datestamp of 2014-06-13.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: 0.2207
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: high affinity nerve growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4aoja_
  • Chain 'B':
    Compound: high affinity nerve growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4aojb_
  • Chain 'C':
    Compound: high affinity nerve growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4aojc_
  • Heterogens: V4Z, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4aojA (A:)
gamgsgsslsptegkgsglqghiienpqyfsdacvhhikrrdivlkwelgegafgkvfla
echnllpeqdkmlvavkalkeasesarqdfqreaelltmlqhqhivrffgvctegrpllm
vfeymrhgdlnrflrshgpdakllaggedvapgplglgqllavasqvaagmvylaglhfv
hrdlatrnclvgqglvvkigdfgmsrdiystdyyrvggrtmlpirwmppesilyrkftte
sdvwsfgvvlweiftygkqpwyqlsnteaidcitqgrelerpracppevyaimrgcwqre
pqqrhsikdvharlqalaqappvyldvlg

    Sequence, based on observed residues (ATOM records): (download) 
    >4aojA (A:)
acvhhikrrdivlkwelgegafgkvflaechnllpkmlvavkalkeasesarqdfqreae
lltmlqhqhivrffgvctegrpllmvfeymrhgdlnrflrshgpdpgplglgqllavasq
vaagmvylaglhfvhrdlatrnclvgqglvvkigdfgtmlpirwmppesilyrkfttesd
vwsfgvvlweiftygkqpwyqlsnteaidcitqgrelerpracppevyaimrgcwqrepq
qrhsikdvharlqalaqapp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4aojB (B:)
gamgsgsslsptegkgsglqghiienpqyfsdacvhhikrrdivlkwelgegafgkvfla
echnllpeqdkmlvavkalkeasesarqdfqreaelltmlqhqhivrffgvctegrpllm
vfeymrhgdlnrflrshgpdakllaggedvapgplglgqllavasqvaagmvylaglhfv
hrdlatrnclvgqglvvkigdfgmsrdiystdyyrvggrtmlpirwmppesilyrkftte
sdvwsfgvvlweiftygkqpwyqlsnteaidcitqgrelerpracppevyaimrgcwqre
pqqrhsikdvharlqalaqappvyldvlg

    Sequence, based on observed residues (ATOM records): (download) 
    >4aojB (B:)
acvhhikrrdivlkwelgegafgkvflaechnllpkmlvavkalkeasesarqdfqreae
lltmlqhqhivrffgvctegrpllmvfeymrhgdlnrflrshgpdgplglgqllavasqv
aagmvylaglhfvhrdlatrnclvgqglvvkigdflpirwmppesilyrkfttesdvwsf
gvvlweiftygkqpwyqlsnteaidcitqgrelerpracppevyaimrgcwqrepqqrhs
ikdvharlqalaqappvy

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4aojC (C:)
gamgsgsslsptegkgsglqghiienpqyfsdacvhhikrrdivlkwelgegafgkvfla
echnllpeqdkmlvavkalkeasesarqdfqreaelltmlqhqhivrffgvctegrpllm
vfeymrhgdlnrflrshgpdakllaggedvapgplglgqllavasqvaagmvylaglhfv
hrdlatrnclvgqglvvkigdfgmsrdiystdyyrvggrtmlpirwmppesilyrkftte
sdvwsfgvvlweiftygkqpwyqlsnteaidcitqgrelerpracppevyaimrgcwqre
pqqrhsikdvharlqalaqappvyldvlg

    Sequence, based on observed residues (ATOM records): (download) 
    >4aojC (C:)
acvhhikrrdivlkwelgegafgkvflaechnllpqdkmlvavkalkeasesarqdfqre
aelltmlqhqhivrffgvctegrpllmvfeymrhgdlnrflrshgpdgplglgqllavas
qvaagmvylaglhfvhrdlatrnclvgqglvvkigdfgmmlpirwmppesilyrkfttes
dvwsfgvvlweiftygkqpwyqlsnteaidcitqgrelerpracppevyaimrgcwqrep
qqrhsikdvharlqalaqapp