PDB entry 4ajr

View 4ajr on RCSB PDB site
Description: 3D structure of E. coli Isocitrate Dehydrogenase K100M mutant in complex with alpha-ketoglutarate, magnesium(II) and NADPH - The product complex
Class: oxidoreductase
Keywords: oxidoreductase, oxidative beta-decarboxylation
Deposited on 2012-02-17, released 2012-10-31
The last revision prior to the SCOPe 2.03 freeze date was dated 2012-10-31, with a file datestamp of 2012-10-26.
Experiment type: XRAY
Resolution: 2.69 Å
R-factor: 0.1628
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Isocitrate dehydrogenase [NADP]
    Species: Escherichia coli [TaxId:83333]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P08200 (Start-415)
      • engineered mutation (99)
    Domains in SCOPe 2.03: d4ajra_
  • Heterogens: NMN, NAP, AKG, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ajrA (A:)
meskvvvpaqgkkitlqngklnvpenpiipyiegdgigvdvtpamlkvvdaavekaykge
rkiswmeiytgekstqvygqdvwlpaetldlireyrvaimgplttpvgggirslnvalrq
eldlyiclrpvryyqgtpspvkhpeltdmvifrensediyagiewkadsadaekvikflr
eemgvkkirfpehcgigikpcseegtkrlvraaieyaiandrdsvtlvhkgnimkftega
fkdwgyqlareefggelidggpwlkvknpntgkeivikdviadaflqqillrpaeydvia
cmnlngdyisdalaaqvggigiapganigdecalfeathgtapkyagqdkvnpgsiilsa
emmlrhmgwteaadlivkgmegainaktvtydferlmdgakllkcsefgdaiienm

    Sequence, based on observed residues (ATOM records): (download) 
    >4ajrA (A:)
eskvvvpaqgkkitlqngklnvpenpiipyiegdgigvdvtpamlkvvdaavekaykger
kiswmeiytgekstqvygqdvwlpaetldlireyrvaimgplttpvgggirslnvalrqe
ldlyiclrpvryyqgtpspvkhpeltdmvifrensediyagiewkadsadaekvikflre
emgvkkirfpehcgigikpcseegtkrlvraaieyaiandrdsvtlvhkgnimkftegaf
kdwgyqlareefggelidggpwlkvknpntgkeivikdviadaflqqillrpaeydviac
mnlngdyisdalaaqvggigiapganigdecalfeathgtapkyagqdkvnpgsiilsae
mmlrhmgwteaadlivkgmegainaktvtydferlmdgakllkcsefgdaiienm