PDB entry 4ahq

View 4ahq on RCSB PDB site
Description: Crystal Structure of N-acetylneuraminic acid lyase mutant K165C from Staphylococcus aureus
Class: lyase
Keywords: lyase
Deposited on 2012-02-06, released 2013-01-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2013-03-13, with a file datestamp of 2013-03-08.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.19274
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: n-acetylneuraminate lyase
    Species: STAPHYLOCOCCUS AUREUS SUBSP. AUREUS NCTC 8325 [TaxId:93061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2G160 (6-297)
      • expression tag (5)
      • engineered mutation (169)
    Domains in SCOPe 2.06: d4ahqa1, d4ahqa2
  • Chain 'B':
    Compound: n-acetylneuraminate lyase
    Species: STAPHYLOCOCCUS AUREUS SUBSP. AUREUS NCTC 8325 [TaxId:93061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2G160 (6-297)
      • expression tag (5)
      • engineered mutation (169)
    Domains in SCOPe 2.06: d4ahqb1, d4ahqb2
  • Chain 'C':
    Compound: n-acetylneuraminate lyase
    Species: STAPHYLOCOCCUS AUREUS SUBSP. AUREUS NCTC 8325 [TaxId:93061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2G160 (6-297)
      • engineered mutation (169)
    Domains in SCOPe 2.06: d4ahqc_
  • Chain 'D':
    Compound: n-acetylneuraminate lyase
    Species: STAPHYLOCOCCUS AUREUS SUBSP. AUREUS NCTC 8325 [TaxId:93061]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q2G160 (Start-297)
      • engineered mutation (169)
    Domains in SCOPe 2.06: d4ahqd_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ahqA (A:)
hhhhhhnkdlkglyaallvpfdengqvneqglkqiaqnaieteeldglyvngssgenfll
nteqkkqvfkvakeavgdkvkliaqvgsldlneaielgkyatelgydalsavtpfyypft
feeirdyyfdiieatqnnmiiyaipdltgvnisieqfselfnhekivgvcytapnfflle
rirkafpdklilsgfdemlvqatisgvdgaigstynvngrrarkifdlarqgqiqeayql
qhdsndiietvlsmgiyptlkeilrhrgidaglpkrpfkpfneahrqtldqliakydl

    Sequence, based on observed residues (ATOM records): (download) 
    >4ahqA (A:)
hnkdlkglyaallvpfdengqvneqglkqiaqnaieteeldglyvngssgenfllnteqk
kqvfkvakeavgdkvkliaqvgsldlneaielgkyatelgydalsavtpfyypftfeeir
dyyfdiieatqnnmiiyaipdltgvnisieqfselfnhekivgvcytapnffllerirka
fpdklilsgfdemlvqatisgvdgaigstynvngrrarkifdlarqgqiqeayqlqhdsn
diietvlsmgiyptlkeilrhrgidaglpkrpfkpfneahrqtldqliakydl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ahqB (B:)
hhhhhhnkdlkglyaallvpfdengqvneqglkqiaqnaieteeldglyvngssgenfll
nteqkkqvfkvakeavgdkvkliaqvgsldlneaielgkyatelgydalsavtpfyypft
feeirdyyfdiieatqnnmiiyaipdltgvnisieqfselfnhekivgvcytapnfflle
rirkafpdklilsgfdemlvqatisgvdgaigstynvngrrarkifdlarqgqiqeayql
qhdsndiietvlsmgiyptlkeilrhrgidaglpkrpfkpfneahrqtldqliakydl

    Sequence, based on observed residues (ATOM records): (download) 
    >4ahqB (B:)
hnkdlkglyaallvpfdengqvneqglkqiaqnaieteeldglyvngssgenfllnteqk
kqvfkvakeavgdkvkliaqvgsldlneaielgkyatelgydalsavtpfyypftfeeir
dyyfdiieatqnnmiiyaipdltgvnisieqfselfnhekivgvcytapnffllerirka
fpdklilsgfdemlvqatisgvdgaigstynvngrrarkifdlarqgqiqeayqlqhdsn
diietvlsmgiyptlkeilrhrgidaglpkrpfkpfneahrqtldqliakydl

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4ahqC (C:)
hhhhhhnkdlkglyaallvpfdengqvneqglkqiaqnaieteeldglyvngssgenfll
nteqkkqvfkvakeavgdkvkliaqvgsldlneaielgkyatelgydalsavtpfyypft
feeirdyyfdiieatqnnmiiyaipdltgvnisieqfselfnhekivgvcytapnfflle
rirkafpdklilsgfdemlvqatisgvdgaigstynvngrrarkifdlarqgqiqeayql
qhdsndiietvlsmgiyptlkeilrhrgidaglpkrpfkpfneahrqtldqliakydl

    Sequence, based on observed residues (ATOM records): (download) 
    >4ahqC (C:)
nkdlkglyaallvpfdengqvneqglkqiaqnaieteeldglyvngssgenfllnteqkk
qvfkvakeavgdkvkliaqvgsldlneaielgkyatelgydalsavtpfyypftfeeird
yyfdiieatqnnmiiyaipdltgvnisieqfselfnhekivgvcytapnffllerirkaf
pdklilsgfdemlvqatisgvdgaigstynvngrrarkifdlarqgqiqeayqlqhdsnd
iietvlsmgiyptlkeilrhrgidaglpkrpfkpfneahrqtldqliakydl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >4ahqD (D:)
hhhhhhnkdlkglyaallvpfdengqvneqglkqiaqnaieteeldglyvngssgenfll
nteqkkqvfkvakeavgdkvkliaqvgsldlneaielgkyatelgydalsavtpfyypft
feeirdyyfdiieatqnnmiiyaipdltgvnisieqfselfnhekivgvcytapnfflle
rirkafpdklilsgfdemlvqatisgvdgaigstynvngrrarkifdlarqgqiqeayql
qhdsndiietvlsmgiyptlkeilrhrgidaglpkrpfkpfneahrqtldqliakydl

    Sequence, based on observed residues (ATOM records): (download) 
    >4ahqD (D:)
kdlkglyaallvpfdengqvneqglkqiaqnaieteeldglyvngssgenfllnteqkkq
vfkvakeavgdkvkliaqvgsldlneaielgkyatelgydalsavtpfyypftfeeirdy
yfdiieatqnnmiiyaipdltgvnisieqfselfnhekivgvcytapnffllerirkafp
dklilsgfdemlvqatisgvdgaigstynvngrrarkifdlarqgqiqeayqlqhdsndi
ietvlsmgiyptlkeilrhrgidaglpkrpfkpfneahrqtldqliakydl