PDB entry 4ahk

View 4ahk on RCSB PDB site
Description: K54E - Angiogenin mutants and amyotrophic lateral sclerosis - a biochemical and biological analysis
Class: hydrolase
Keywords: hydrolase, amyotrophic, lateral sclerosis, neovascularisation
Deposited on 2012-02-06, released 2012-10-10
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-10-10, with a file datestamp of 2012-10-05.
Experiment type: XRAY
Resolution: 1.97 Å
R-factor: 0.2171
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: angiogenin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03950
      • engineered mutation (53)
    Domains in SCOPe 2.05: d4ahka_
  • Chain 'B':
    Compound: angiogenin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P03950
      • engineered mutation (53)
    Domains in SCOPe 2.05: d4ahkb_
  • Heterogens: TAR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4ahkA (A:)
qdnsrythfltqhydakpqgrddrycesimrrrgltspckdintfihgnkrsieaicenk
ngnphrenlriskssfqvttcklhggspwppcqyratagfrnvvvacenglpvhldqsif
rrp

    Sequence, based on observed residues (ATOM records): (download) 
    >4ahkA (A:)
nsrythfltqhydakpqgrddrycesimrrrgltspckdintfihgnkrsieaicenkng
nphrenlriskssfqvttcklhggspwppcqyratagfrnvvvacenglpvhldqsifrr

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4ahkB (B:)
qdnsrythfltqhydakpqgrddrycesimrrrgltspckdintfihgnkrsieaicenk
ngnphrenlriskssfqvttcklhggspwppcqyratagfrnvvvacenglpvhldqsif
rrp

    Sequence, based on observed residues (ATOM records): (download) 
    >4ahkB (B:)
nsrythfltqhydakpqgrddrycesimrrrgltspckdintfihgnkrsieaicenkng
nphrenlriskssfqvttcklhggspwppcqyratagfrnvvvacenglpvhldqsifrr