PDB entry 4agu

View 4agu on RCSB PDB site
Description: crystal structure of the human cdkl1 kinase domain
Class: transferase
Keywords: transferase, phospho-mimetic, kinase
Deposited on 2012-01-31, released 2012-02-08
The last revision prior to the SCOPe 2.03 freeze date was dated 2012-02-08, with a file datestamp of 2012-02-03.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.1885
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cyclin-dependent kinase-like 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q00532
      • variant (274)
    Domains in SCOPe 2.03: d4agua_
  • Chain 'B':
    Compound: cyclin-dependent kinase-like 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q00532
      • variant (274)
    Domains in SCOPe 2.03: d4agub_
  • Chain 'C':
    Compound: cyclin-dependent kinase-like 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q00532
      • variant (274)
    Domains in SCOPe 2.03: d4aguc_
  • Heterogens: D15, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4aguA (A:)
mmekyekigkigegsygvvfkcrnrdtgqivaikkfleseddpvikkialreirmlkqlk
hpnlvnllevfrrkrrlhlvfeycdhtvlheldryqrgvpehlvksitwqtlqavnfchk
hncihrdvkpenilitkhsviklcdfgfarlltgpsdyyddevatrwyrspellvgdtqy
gppvdvwaigcvfaellsgvplwpgksdvdqlylirktlgdliprhqqvfstnqyfsgvk
ipdpedmeplelkfpnisypalgllkgclhmdpterltceqllhhpyfenireiedlake
hdkpaenlyfq

    Sequence, based on observed residues (ATOM records): (download) 
    >4aguA (A:)
ekyekigkigegsygvvfkcrnrdtgqivaikkflesedpvikkialreirmlkqlkhpn
lvnllevfrrkrrlhlvfeycdhtvlheldryqrgvpehlvksitwqtlqavnfchkhnc
ihrdvkpenilitkhsviklcdfgfarlltrwyrspellvgdtqygppvdvwaigcvfae
llsgvplwpgksdvdqlylirktlgdliprhqqvfstnqyfsgvkipdpedmeplelkfp
nisypalgllkgclhmdpterltceqllhhpyfenir

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4aguB (B:)
mmekyekigkigegsygvvfkcrnrdtgqivaikkfleseddpvikkialreirmlkqlk
hpnlvnllevfrrkrrlhlvfeycdhtvlheldryqrgvpehlvksitwqtlqavnfchk
hncihrdvkpenilitkhsviklcdfgfarlltgpsdyyddevatrwyrspellvgdtqy
gppvdvwaigcvfaellsgvplwpgksdvdqlylirktlgdliprhqqvfstnqyfsgvk
ipdpedmeplelkfpnisypalgllkgclhmdpterltceqllhhpyfenireiedlake
hdkpaenlyfq

    Sequence, based on observed residues (ATOM records): (download) 
    >4aguB (B:)
kyekigkigegsygvvfkcrnrdtgqivaikkflesdpvikkialreirmlkqlkhpnlv
nllevfrrkrrlhlvfeycdhtvlheldryqrgvpehlvksitwqtlqavnfchkhncih
rdvkpenilitkhsviklcdfgfarlltrwyrspellvgdtqygppvdvwaigcvfaell
sgvplwpgksdvdqlylirktlgdliprhqqvfstnqyfsgvkipdpedmeplelkfpni
sypalgllkgclhmdpterltceqllhhpyfenire

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4aguC (C:)
mmekyekigkigegsygvvfkcrnrdtgqivaikkfleseddpvikkialreirmlkqlk
hpnlvnllevfrrkrrlhlvfeycdhtvlheldryqrgvpehlvksitwqtlqavnfchk
hncihrdvkpenilitkhsviklcdfgfarlltgpsdyyddevatrwyrspellvgdtqy
gppvdvwaigcvfaellsgvplwpgksdvdqlylirktlgdliprhqqvfstnqyfsgvk
ipdpedmeplelkfpnisypalgllkgclhmdpterltceqllhhpyfenireiedlake
hdkpaenlyfq

    Sequence, based on observed residues (ATOM records): (download) 
    >4aguC (C:)
ekyekigkigegsygvvfkcrnrdtgqivaikkfleseddpvikkialreirmlkqlkhp
nlvnllevfrrkrrlhlvfeycdhtvlheldryqrgvpehlvksitwqtlqavnfchkhn
cihrdvkpenilitkhsviklcdfgfarlltrwyrspellvgdtqygppvdvwaigcvfa
ellsgvplwpgksdvdqlylirktlgdliprhqqvfstnqyfsgvkipdpedmeplelkf
pnisypalgllkgclhmdpterltceqllhhpyfenir