PDB entry 4af3
View 4af3 on RCSB PDB site
Description: Human Aurora B Kinase in complex with INCENP and VX-680
Class: transferase/inhibitor
Keywords: transferase-inhibitor complex, aurkb
Deposited on
2012-01-16, released
2012-04-11
The last revision prior to the SCOPe 2.02 freeze date was dated
2012-09-26, with a file datestamp of
2012-09-21.
Experiment type: XRAY
Resolution: 2.75 Å
R-factor: 0.20776
AEROSPACI score: 0.29
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: aurora kinase b
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.02: d4af3a_ - Chain 'D':
Compound: Inner centromere protein
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Heterogens: VX6, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4af3A (A:)
smqkvmenssgtpdiltrhftiddfeigrplgkgkfgnvylarekkshfivalkvlfksq
iekegvehqlrreieiqahlhhpnilrlynyfydrrriylileyaprgelykelqksctf
deqrtatimeeladalmychgkkvihrdikpenlllglkgelkiadfgwsvhapslrrkt
mcgtldylppemiegrmhnekvdlwcigvlcyellvgnppfesashnetyrrivkvdlkf
pasvptgaqdliskllrhnpserlplaqvsahpwvransrrvlppsalqsva
Sequence, based on observed residues (ATOM records): (download)
>4af3A (A:)
rhftiddfeigrplgkgkfgnvylarekkshfivalkvlfksqiekegvehqlrreieiq
ahlhhpnilrlynyfydrrriylileyaprgelykelqksctfdeqrtatimeeladalm
ychgkkvihrdikpenlllglkgelkiadfgldylppemiegrmhnekvdlwcigvlcye
llvgnppfesashnetyrrivkvdlkfpasvptgaqdliskllrhnpserlplaqvsahp
wvransrrvlpps
- Chain 'D':
No sequence available.