PDB entry 4acp

View 4acp on RCSB PDB site
Description: Deactivation of human IgG1 Fc by endoglycosidase treatment
Class: immune system
Keywords: immune system, igg, antibody, kifunensine
Deposited on 2011-12-16, released 2012-04-25
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-06-13, with a file datestamp of 2012-06-08.
Experiment type: XRAY
Resolution: 2.49 Å
R-factor: 0.1968
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ig gamma-1 chain C region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01857
      • cloning artifact (177)
    Domains in SCOPe 2.05: d4acpa1, d4acpa2
  • Chain 'B':
    Compound: Ig gamma-1 chain C region
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01857
      • cloning artifact (177)
    Domains in SCOPe 2.05: d4acpb1, d4acpb2
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4acpA (A:)
gtkscdkthtcppcpapellggpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkf
nwyvdgvevhnaktkpreeqynstyrvvsvltvlhqdwlngkeykckvsnkalpapiekt
iskakgqprepqvytlppsrdeltknqvsltclvkgfypsdiavewesngqpennykatp
pvldsdgsfflyskltvdksrwqqgnvfscsvmhealhnhytqkslslspggtkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4acpA (A:)
psvflfppkpkdtlmisrtpevtcvvvdvshpevkfnwyvdgvevhnaktkpreeqtyrv
vsvltvlhqdwlngkeykckvsnkpiektiskakgqprepqvytlppsrdeltknqvslt
clvkgfypsdiavewesngqpennykatppvldsdgsfflyskltvdksrwqqgnvfscs
vmhealhnhytqkslsls

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4acpB (B:)
gtkscdkthtcppcpapellggpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkf
nwyvdgvevhnaktkpreeqynstyrvvsvltvlhqdwlngkeykckvsnkalpapiekt
iskakgqprepqvytlppsrdeltknqvsltclvkgfypsdiavewesngqpennykatp
pvldsdgsfflyskltvdksrwqqgnvfscsvmhealhnhytqkslslspggtkhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >4acpB (B:)
gpsvflfppkpkdtlmisrtpevtcvvvdvshedpevkfnwyvdgvevhnaktkpreeqy
nstyrvvsvltvlhqdwlngkeykckvsnkalpapiektiskakgqprepqvytlppsrd
eltknqvsltclvkgfypsdiavewesngqpennykatppvldsdgsfflyskltvdksr
wqqgnvfscsvmhealhnhytqkslsls