PDB entry 4a9t

View 4a9t on RCSB PDB site
Description: crystal structure of human chk2 in complex with benzimidazole carboxamide inhibitor
Class: transferase
Keywords: transferase
Deposited on 2011-11-28, released 2012-10-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-11-07, with a file datestamp of 2012-11-02.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: 0.1905
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine-protein kinase chk2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot O96017 (7-End)
      • expression tag (6)
    Domains in SCOPe 2.08: d4a9ta1, d4a9ta2
  • Heterogens: A9T, NO3, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4a9tA (A:)
gplgshmsvypkalrdeyimsktlgsgacgevklaferktckkvaikiiskrkfaigsar
eadpalnveteieilkklnhpciikiknffdaedyyivlelmeggelfdkvvgnkrlkea
tcklyfyqmllavqylhengiihrdlkpenvllssqeedclikitdfghskilgetslmr
tlcgtptylapevlvsvgtagynravdcwslgvilficlsgyppfsehrtqvslkdqits
gkynfipevwaevsekaldlvkkllvvdpkarftteealrhpwlqdedmkrkfqdllsee
nestalpqvlaqpstsrkrpregeaegae

    Sequence, based on observed residues (ATOM records): (download) 
    >4a9tA (A:)
msvypkalrdeyimsktlgsgevklaferktckkvaikiiskpalnveteieilkklnhp
ciikiknffdaedyyivlelmeggelfdkvvgnkrlkeatcklyfyqmllavqylhengi
ihrdlkpenvllssqeedclikitdfghskilgetslmrtlcgtptylapevlvsvgtag
ynravdcwslgvilficlsgyppfsehrtqvslkdqitsgkynfipevwaevsekaldlv
kkllvvdpkarftteealrhpwlqdedmkrkfqdllseenestalpqvla