PDB entry 4a9r

View 4a9r on RCSB PDB site
Description: crystal structure of human chk2 in complex with benzimidazole carboxamide inhibitor
Class: transferase
Keywords: transferase, kinase
Deposited on 2011-11-28, released 2012-10-10
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-11-07, with a file datestamp of 2012-11-02.
Experiment type: XRAY
Resolution: 2.85 Å
R-factor: 0.1865
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine/threonine-protein kinase chk2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d4a9ra_
  • Heterogens: NO3, RU5, EDO, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4a9rA (A:)
gplgshmsvypkalrdeyimsktlgsgacgevklaferktckkvaikiiskrkfaigsar
eadpalnveteieilkklnhpciikiknffdaedyyivlelmeggelfdkvvgnkrlkea
tcklyfyqmllavqylhengiihrdlkpenvllssqeedclikitdfghskilgetslmr
tlcgtptylapevlvsvgtagynravdcwslgvilficlsgyppfsehrtqvslkdqits
gkynfipevwaevsekaldlvkkllvvdpkarftteealrhpwlqdedmkrkfqdllsee
nestalpqvlaqpstsrkrpregeaegae

    Sequence, based on observed residues (ATOM records): (download) 
    >4a9rA (A:)
svypkalrdeyimsktlevklaferktckkvaikiiskpalnveteieilkklnhpciik
iknffdaedyyivlelmeggelfdkvvgnkrlkeatcklyfyqmllavqylhengiihrd
lkpenvllssqeedclikitdfghskilgetslmrtlcgtptylapevlvsvgtagynra
vdcwslgvilficlsgyppfsehrtqvslkdqitsgkynfipevwaevsekaldlvkkll
vvdpkarftteealrhpwlqdedmkrkfqdllseenestalpqvla