PDB entry 4a9h

View 4a9h on RCSB PDB site
Description: N-TERMINAL BROMODOMAIN OF HUMAN BRD2 WITH 1-(2-methyl-1,2,3,4-tetrahydroquinolin-1-yl)ethan-1-one
Class: signaling protein
Keywords: signaling protein, inhibitor, histone, epigenetic reader
Deposited on 2011-11-26, released 2012-01-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-15, with a file datestamp of 2019-05-10.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4a9ha_
  • Chain 'B':
    Compound: Bromodomain-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4a9hb_
  • Chain 'C':
    Compound: Bromodomain-containing protein 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4a9hc_
  • Heterogens: EDO, TVP, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4a9hA (A:)
gsshhhhhhssglvprgshmsnpkkpgrvtnqlqylhkvvmkalwkhqfawpfrqpvdav
klglpdyhkiikqpmdmgtikrrlennyywaasecmqdfntmftncyiynkptddivlma
qtlekiflqkvasmpqeeqelvvtipknshkkga

    Sequence, based on observed residues (ATOM records): (download) 
    >4a9hA (A:)
vtnqlqylhkvvmkalwkhqfawpfrqpvdavklglpdyhkiikqpmdmgtikrrlenny
ywaasecmqdfntmftncyiynkptddivlmaqtlekiflqkvasmpqeeqe

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >4a9hB (B:)
gsshhhhhhssglvprgshmsnpkkpgrvtnqlqylhkvvmkalwkhqfawpfrqpvdav
klglpdyhkiikqpmdmgtikrrlennyywaasecmqdfntmftncyiynkptddivlma
qtlekiflqkvasmpqeeqelvvtipknshkkga

    Sequence, based on observed residues (ATOM records): (download) 
    >4a9hB (B:)
tnqlqylhkvvmkalwkhqfawpfrqpvdavklglpdyhkiikqpmdmgtikrrlennyy
waasecmqdfntmftncyiynkptddivlmaqtlekiflqkvasmpq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >4a9hC (C:)
gsshhhhhhssglvprgshmsnpkkpgrvtnqlqylhkvvmkalwkhqfawpfrqpvdav
klglpdyhkiikqpmdmgtikrrlennyywaasecmqdfntmftncyiynkptddivlma
qtlekiflqkvasmpqeeqelvvtipknshkkga

    Sequence, based on observed residues (ATOM records): (download) 
    >4a9hC (C:)
tnqlqylhkvvmkalwkhqfawpfrqpvdavklglpdyhkiikqpmdmgtikrrlennyy
waasecmqdfntmftncyiynkptddivlmaqtlekiflqkvasmpq