PDB entry 4a7q
View 4a7q on RCSB PDB site
Description: Structure of human I113T SOD1 mutant complexed with 4-(4-methyl-1,4- diazepan-1-yl)quinazoline in the p21 space group.
Class: oxidoreductase
Keywords: oxidoreductase, amyotrophic lateral sclerosis, antioxidant, disease mutation, metal-binding, zn superoxide dismutase
Deposited on
2011-11-14, released
2012-10-24
The last revision prior to the SCOPe 2.08 freeze date was dated
2013-08-28, with a file datestamp of
2013-08-23.
Experiment type: XRAY
Resolution: 1.22 Å
R-factor: 0.12664
AEROSPACI score: 0.84
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Superoxide dismutase [Cu-Zn]
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P00441 (0-152)
- engineered mutation (112)
Domains in SCOPe 2.08: d4a7qa_ - Chain 'F':
Compound: Superoxide dismutase [Cu-Zn]
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Uniprot P00441 (0-152)
- engineered mutation (112)
Domains in SCOPe 2.08: d4a7qf_ - Heterogens: 4MQ, SO4, CU, ZN, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>4a7qA (A:)
atkavcvlkgdgpvqgiinfeqkesngpvkvwgsikglteglhgfhvhefgdntagctsa
gphfnplsrkhggpkdeerhvgdlgnvtadkdgvadvsiedsvislsgdhcitgrtlvvh
ekaddlgkggneestktgnagsrlacgvigiaq
- Chain 'F':
Sequence; same for both SEQRES and ATOM records: (download)
>4a7qF (F:)
atkavcvlkgdgpvqgiinfeqkesngpvkvwgsikglteglhgfhvhefgdntagctsa
gphfnplsrkhggpkdeerhvgdlgnvtadkdgvadvsiedsvislsgdhcitgrtlvvh
ekaddlgkggneestktgnagsrlacgvigiaq