PDB entry 4a7i
View 4a7i on RCSB PDB site
Description: Factor Xa in complex with a potent 2-amino-ethane sulfonamide inhibitor
Class: hydrolase
Keywords: blood coagulation factor, calcium- binding, egf-like domain, gamma-carboxyglutamic acid, glycoprotein, hydrolase, hydroxylation, serine proteinase, serine protease
Deposited on
2011-11-14, released
2012-02-01
The last revision prior to the SCOPe 2.07 freeze date was dated
2012-02-01, with a file datestamp of
2012-01-27.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.198
AEROSPACI score: 0.34
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: factor x light chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4a7ia_ - Chain 'B':
Compound: activated factor xa heavy chain xa
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.07: d4a7ib_ - Heterogens: CA, A7I, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>4a7iA (A:)
ykdgdqcetspcqnqgkckdglgeytctclegfegkncelftrklcsldngdcdqfchee
qnsvvcscargytladngkaciptgpypcgkqtler
Sequence, based on observed residues (ATOM records): (download)
>4a7iA (A:)
rklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle
- Chain 'B':
Sequence, based on SEQRES records: (download)
>4a7iB (B:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
kshapevitssplk
Sequence, based on observed residues (ATOM records): (download)
>4a7iB (B:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt