PDB entry 4a7i

View 4a7i on RCSB PDB site
Description: Factor Xa in complex with a potent 2-amino-ethane sulfonamide inhibitor
Class: hydrolase
Keywords: blood coagulation factor, calcium- binding, egf-like domain, gamma-carboxyglutamic acid, glycoprotein, hydrolase, hydroxylation, serine proteinase, serine protease
Deposited on 2011-11-14, released 2012-02-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-02-01, with a file datestamp of 2012-01-27.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.198
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: factor x light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4a7ia_
  • Chain 'B':
    Compound: activated factor xa heavy chain xa
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d4a7ib_
  • Heterogens: CA, A7I, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4a7iA (A:)
    ykdgdqcetspcqnqgkckdglgeytctclegfegkncelftrklcsldngdcdqfchee
    qnsvvcscargytladngkaciptgpypcgkqtler
    

    Sequence, based on observed residues (ATOM records): (download)
    >4a7iA (A:)
    rklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >4a7iB (B:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktrglpka
    kshapevitssplk
    

    Sequence, based on observed residues (ATOM records): (download)
    >4a7iB (B:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt