PDB entry 4a6c

View 4a6c on RCSB PDB site
Description: Stereoselective Synthesis, X-ray Analysis, and Biological Evaluation of a New Class of Lactam Based HIV-1 Protease Inhibitors
Class: hydrolase
Keywords: hydrolase, gamma-butyrol-lactam
Deposited on 2011-11-01, released 2012-05-09
The last revision prior to the SCOPe 2.05 freeze date was dated 2012-05-09, with a file datestamp of 2012-05-04.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: 0.23
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: pol protein
  Species: HUMAN IMMUNODEFICIENCY VIRUS [TaxId:12721]
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q8Q3H0
    • conflict (62)
    • conflict (81)
    • conflict (83)
  Domains in SCOPe 2.05: d4a6ca_
• Chain 'B':
  Compound: pol protein
  Species: HUMAN IMMUNODEFICIENCY VIRUS [TaxId:12721]
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q8Q3H0 (0-98)
    • conflict (62)
    • conflict (81)
    • conflict (83)
  Domains in SCOPe 2.05: d4a6cb_
• Heterogens: QG9, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4a6cA (A:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qipieicghkaigtvlvgptptnvigrnlltqigctlnf
  

  
  
• Chain 'B':
  Sequence; same for both SEQRES and ATOM records: (download)
  

  >4a6cB (B:)
  pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
  qipieicghkaigtvlvgptptnvigrnlltqigctlnf