PDB entry 4a2r

View 4a2r on RCSB PDB site
Description: Structure of the engineered retro-aldolase RA95.5-5
Class: lyase
Keywords: lyase, engineered enzyme, directed evolution
Deposited on 2011-09-28, released 2012-11-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-15, with a file datestamp of 2019-05-10.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: N/A
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: indole-3-glycerol phosphate synthase
    Species: Sulfolobus solfataricus [TaxId:2287]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q06121 (Start-244)
      • engineered mutation (9)
      • engineered mutation (21-22)
      • engineered mutation (42)
      • engineered mutation (50)
      • engineered mutation (52)
      • engineered mutation (69)
      • engineered mutation (82)
      • engineered mutation (94)
      • engineered mutation (109)
      • engineered mutation (158)
      • engineered mutation (177)
      • engineered mutation (179)
      • engineered mutation (181-183)
      • engineered mutation (186)
      • engineered mutation (209-210)
      • engineered mutation (232)
      • expression tag (245-247)
    Domains in SCOPe 2.08: d4a2ra1, d4a2ra2
  • Heterogens: 3NK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4a2rA (A:)
mprylkgwledvvqlslrrpsvhasrqrpiislnerilefnksnitaiiayytrkspsgl
dverdpieyakfmeryavglsikteekyfngsyemlrkiassvsipilmndfivkesqid
daynlgadtvllivkiltereleslleyarsygmeplilindendldialrigarfisif
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    Sequence, based on observed residues (ATOM records): (download) 
    >4a2rA (A:)
prylkgwledvvqlslrrpsvhasrqrpiislnerilefnksnitaiiayytrkspsgld
verdpieyakfmeryavglsikteekyfngsyemlrkiassvsipilmndfivkesqidd
aynlgadtvllivkiltereleslleyarsygmeplilindendldialrigarfisifs
mnfetgeinkenqrklismipsnvvkvaklgiserneieelrklgvnaflissslmrnpe
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