SCOPe Funding Alert: SCOPe support from the NIH ended in April 2016. John-Marc Chandonia is the primary maintainer and has continued to develop SCOPe using vacation time. Three proposals to the NIH for continued funding have been unsuccessful. If our current NIH proposal is not funded, SCOPe will shut down permanently in Summer 2017 as Dr. Chandonia will need to seek a new position.
You accessed the SCOPe website through a deprecated URL; see Help for SCOPe 2.01 for more info on linking to SCOPe.
Showing results for SCOPe 2.06; you can access the page in SCOP 1.75 here.

PDB entry 4K98

View 4K98 on RCSB PDB site
Description: Structure of Ternary Complex of cGAS with dsDNA and Bound 5 -pppG(2 ,5 )pG
Deposited on 2013-04-19, released 2013-05-15
The last revision was dated 2013-08-28, with a file datestamp of 2013-08-23.
Experiment type: XRAY
Resolution: 1.94 Å
R-factor: 0.159
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cyclic GMP-AMP synthase
    Species: Mus musculus [TaxId:10090]
    Gene: Mb21d1
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: DNA-f
    Species: synthetic, synthetic
  • Chain 'E':
    Compound: DNA-r
    Species: synthetic, synthetic
  • Heterogens: ZN, MG, GTP, G, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.06, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >4k98A (A:)
    spdklkkvldklrlkrkdiseaaetvnkvverllrrmqkresefkgveqlntgsyyehvk
    isapnefdvmfklevprielqeyyetgafylvkfkriprgnplshflegevlsatkmlsk
    frkiikeevkeikdidvsvekekpgspavtllirnpeeisvdiilaleskgswpistkeg
    lpiqgwlgtkvrtnlrrepfylvpknakdgnsfqgetwrlsfshtekyilnnhgiektcc
    essgakccrkeclklmkylleqlkkefqeldafcsyhvktaifhmwtqdpqdsqwdprnl
    sscfdkllaffleclrtekldhyfipkfnlfsqelidrkskeflskkieyernngfpifd
    kl
    

    Sequence, based on observed residues (ATOM records):
    >4k98A (A:)
    klkkvldklrlkrkdiseaaetvnkvverllrrmqkresefkgveqlntgsyyehvkisa
    pnefdvmfklevprielqeyyetgafylvkfkgnplshflegevlsatkmlskfrkiike
    evkeikdidvsvekekpgspavtllirnpeeisvdiilaleskgswpistkeglpiqgwl
    gtkvrtnlrrepfylvpknakdgnsfqgetwrlsfshtekyilnnhgiektccessgakc
    crkeclklmkylleqlkkefqeldafcsyhvktaifhmwtqdpqdsqwdprnlsscfdkl
    laffleclrtekldhyfipkfnlfsqelidrkskeflskkieyernngfpifdk
    

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    No sequence available.